Evidence map›Paper›PMID 26571385›Full record

ArticlePloS one2015

Influence of Fatty Liver on the Severity and Clinical Outcome in Acute Pancreatitis.

Chunfang Xu, Zhenguo Qiao, Yongda Lu, Deqing Zhang, Zhenyu Jia, Xiaohui Zhuang, Yuqi Shi, Ting Xu, Lihua Xing, Jiaqing Shen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chunfang XuDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Zhenguo QiaoDepartment of Gastroenterology, Affiliated Wujiang Hospital of Nantong University, Jiangsu, China.
Yongda LuDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Deqing ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Zhenyu JiaDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Xiaohui ZhuangDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Yuqi ShiDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Ting XuDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Lihua XingDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Jiaqing ShenDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Soochow University · CNFirst Affiliated Hospital of Soochow University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis (AP) is a common disease in the department of gastroenterology with variable severity, from being mild and self-limited to severe and fatal. The early diagnosis and accurate prediction of AP severity are of great importance. Our primary observation showed that fatty liver (FL) was frequently detected in patients with AP. In this retrospective study, we aimed to evaluate the relation between FL and the severity and outcomes of AP. The medical records of 2671 patients with AP were reviewed retrospectively, and characteristics of AP patients were recorded. FL was assessed by abdominal CT scan, and AP patients were categorized by the occurrence of FL for the analysis. The variation of mortality, clinical severity and the appearance of CT were analyzed between the non-FL group and FL groups. Compared with patients without FL, an obviously higher rate of death and higher frequency of severe AP (SAP) and necrotizing AP (ANP) were observed in patients with FL, as well as the incidence of local complications and systemic complications. Taking obesity into consideration, a higher rate of death and more severe AP were found in patients with FL, no matter whether they were obese or not. Alcoholic fatty liver (AFL) and non-alcoholic fatty liver (NAFL) were also separated for comparison in this study; the incidence of ANP and the clinical severity had no significant difference between the AFL and NAFL groups. In conclusion, FL could influence the severity and clinical outcome and may play a prognostic role in AP. This study is of clinical significance, because few reports have been previously issued on FL and AP.

Indexed as

AdultAgedComorbidityFatty LiverFemaleHumansIncidenceMaleMiddle AgedObesityOdds RatioPancreatitisPancreatitis, Acute NecrotizingPrognosisRadiography, AbdominalRetrospective Studies

Identifiers

PMID26571385
PMCPMC4646451
OpenAlexW2196848171

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.