ArticleSubstance abuse2016
Screening and evaluation of hepatitis C virus infection in pregnant women on opioid maintenance therapy: A retrospective cohort study.
Article in Substance abuse, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 49 citations in OpenAlex.
- Care strategies for pregnant people and women living with hepatitis C in North America.AJOG global reports · 2026Article
- Hepatitis C virus in childhood and pregnancy.Infectious diseases & immunity · 2025Review
- Sofosbuvir/Velpatasvir Pharmacokinetics, Safety, and Efficacy in Pregnant People With Hepatitis C Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Hepatitis C virus detection and management after implementation of universal screening in pregnancy.AJOG global reports · 2024Article
- Investigating the neurobiology of maternal opioid use disorder and prenatal opioid exposure using brain organoid technology.Frontiers in cellular neuroscience · 2024Review
- Evidence for Implementation: HIV/HCV Coinfection and Pregnancy.Current HIV/AIDS reports · 2023Review
- Pediatric Primary Care Diagnoses Among Children with Intrauterine Opioid Exposure.Journal of health care for the poor and underserved · 2023Article
- Cost-effectiveness of Antenatal Rescreening Among Pregnant Women for Hepatitis C in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Innovations in Hepatitis C Screening and Treatment.Hepatology communications · 2021Review
- Experiences and Perspectives From Women Taking Investigational Therapy for Hepatitis C Virus During Pregnancy.Substance abuse : research and treatment · 2021Article
- Hepatitis C Virus in Pregnancy: Are We Ready for Test and Treat?The Journal of infectious diseases · 2020Article
- Ledipasvir plus sofosbuvir in pregnant women with hepatitis C virus infection: a phase 1 pharmacokinetic study.The Lancet. Microbe · 2020Article
- CDC Recommendations for Hepatitis C Screening Among Adults - United States, 2020.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2020Article
- Hepatitis C Testing Among Perinatally Exposed Infants.Pediatrics · 2020Article
- Estimates of Prenatal HIV, Hepatitis B Virus, and Hepatitis C Virus Testing Among Pregnant People Enrolled in Wisconsin Medicaid, 2011-2015.Maternal and child health journal · 2020Article
- Cost-effectiveness of Universal Hepatitis C Virus Screening of Pregnant Women in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Opioid epidemic and liver disease.JHEP reports : innovation in hepatology · 2019Review
- Increasing Prevalence of Chronic Hepatitis C Virus Infection in a Southern Academic Obstetrical Clinic.Southern medical journal · 2019Article
- Short-Term Effects and Long-Term Cost-Effectiveness of Universal Hepatitis C Testing in Prenatal Care.Obstetrics and gynecology · 2019Article
- Prenatal intent and postpartum receipt of long-acting reversible contraception among women receiving medication-assisted treatment for opioid use disorder.Contraception · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe purpose of this study was to describe the delivery of prenatal care services to women with opioid use disorder (OUD) on opioid maintenance therapy at high risk for hepatitis C virus (HCV) infection.
methodsWe conducted a retrospective cohort evaluation of 791 pregnant women with OUD from 2009 to 2012. HCV screening was defined as documentation of (a) an anti-HCV antibody test or (b) a provider discussion regarding a known HCV diagnosis during pregnancy. Multivariate logistic regression was used to identify predictors of HCV screening during pregnancy.
resultsAmong 791 pregnant women with OUD, 611 (77.2%) were screened for HCV infection and 369/611 (60.4%) were HCV positive. In multivariable analysis, patients who were married (odds ratio [OR] = 0.52; 95% confidence interval [CI] = 0.29, 0.91), used buprenorphine (OR = 0.45; 95% CI = 0.28, 0.71), and were cared for by private practice providers (OR = 0.29; 95% CI = 0.19, 0.45) were significantly less likely to be screened. In contrast, patients who used benzodiazepines (OR = 1.72; 95% CI = 1.02, 2.92), intravenous (IV) opioids (OR = 6.15; 95% CI = 3.96, 9.56), had legal problems (OR = 2.23; 95% CI = 1.12, 4.45), had children not in their custody (OR = 1.81; 95% CI = 1.01, 3.24), and who had a partner with substance abuse history (OR = 2.38; 95% CI = 1.23, 4.59) were significantly more likely to be screened. Of 369 HCV-positive patients, a new diagnosis of HCV was made during pregnancy for 108 (29.3%) patients. Only 94 (25.5%) had HCV viral load testing, 61 (16.5%) had HCV genotype testing, and 38 (10.4%) received an immunization for hepatitis A. Although 285 (77.2%) patients were referred to hepatology, only 71 (24.9%) attended the consultation. Finally, only 6 (1.6%) patients received HCV treatment 1 year following delivery.
conclusionsPrenatal care approaches to HCV infection remain inconsistent, and the majority of patients diagnosed with HCV infection during pregnancy do not receive treatment after delivery.
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