Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2016
The Effects of Acupuncture on Cerebral Blood Flow in Post-Stroke Patients: A Randomized Controlled Trial.
Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 40 citations in OpenAlex.
- Efficacy of Acupuncture Combined with Local Anesthesia in Ischemic Stroke Patients with Carotid Artery Stenting: A Prospective Randomized Trial.Chinese journal of integrative medicine · 2020Trial
- The design and reporting of sham acupuncture and its association with the efficacy in acupuncture randomized controlled trials for migraine.BMC complementary medicine and therapies · 2026Article
- Acorus tatarinowii volatile oil inhalation combined with Fengchi (GB20) acupuncture enhances cognitive recovery in post-stroke patients.American journal of translational research · 2026Article
- Acupuncture for stroke survivors with cardiovascular comorbidities: protocol of a pooled analysis of randomized controlled trials.Frontiers in neurology · 2025Article
- Effect of the combination of acupuncture based on Yuan-Luo Da-Jie-Jing and repetitive transcranial magnetic stimulation on type 1 complex regional pain after stroke: a randomized controlled trial protocol.Frontiers in neurology · 2025Article
- Article
- Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Article
- Global trends and hotspots in research on acupuncture for stroke: a bibliometric and visualization analysis.European journal of medical research · 2023Article
- Waggle needling Yanglingquan (GB34) enhances cerebral blood flow and ameliorates condition of spastic paresis in rats with middle cerebral artery occlusion induced by surgical nylon suture.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Article
- Neural control of cerebral blood flow: scientific basis of scalp acupuncture in treating brain diseases.Frontiers in neuroscience · 2023Review
- Using radial pulse wave as hemodynamic measurements to quantify effects of acupuncture therapy for patients with traumatic brain injury and ischemia stroke.Journal of traditional and complementary medicine · 2022Article
- Effects of Acupuncture-Related Therapies in the Rehabilitation of Patients with Post-Stroke Aphasia-A Network Meta-Analysis of Randomized Controlled Trials.Brain sciences · 2022Review
- Efficacy of Acupuncture Treatment for Incidence of Poststroke Comorbidities: A Systematic Review and Meta-Analysis of Nationalized Cohort Studies.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Acupuncture Treatment is Associated with Reduced Dementia Risk in Patients with Migraine: A Propensity-Score-Matched Cohort Study of Real-World Data.Neuropsychiatric disease and treatment · 2022Article
- Potential mechanisms of acupuncture in enhancing cerebral perfusion of ischemic stroke.Frontiers in neurology · 2022Review
- Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Efficacy and safety of acupuncture for posterior circulation ischemic vertigo: A protocol for systematic review and meta-analysis.Medicine · 2020Article
- Electroacupuncture ameliorates learning and memory deficits via hippocampal 5-HT1A receptors and the PKA signaling pathway in rats with ischemic stroke.Metabolic brain disease · 2020Article
- Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis.Neural plasticity · 2020Article
- Acupuncture Enhances Communication between Cortices with Damaged White Matters in Poststroke Motor Impairment.Evidence-based complementary and alternative medicine : eCAM · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectiveStroke is a major cause of disability and death in the Western world. Studies have shown a direct relationship between specific mental and motor activity and changes in cerebral blood flow. Acupuncture is often used in post-stroke patients, but there is a lack of sham-controlled studies evaluating the effects of acupuncture on cerebral blood flow following a stroke. This pilot concept-assessment study sought to evaluate the effects of true acupuncture on cerebral blood flow velocity compared with sham acupuncture and lay a foundation for future work in this field.
methodsSeventeen inpatients (age range, 44-79 years) 1-3 months post-stroke were allocated to acupuncture at true acupuncture (TA) points or at sham acupuncture (SA) points. The treatment was 20 minutes long. Transcranial Doppler ultrasonography was used to measure mean flow velocity (MFV) and peak flow velocity (PFV) at both healthy and damaged hemispheres before (T0), in the middle of (T15), and 5 minutes after (T25) treatment. Blood pressure was measured at T0 and T25.
resultsA statistically significant (p < 0.04) MFV increase in both hemispheres was found during and after TA; this increase was higher than that seen with SA (p < 0.035). Acupuncture had no significant effect on PFV. Systolic blood pressure significantly decreased after acupuncture (p < 0.005) in a similar manner for both TA and SA. National Institutes of Health Stroke Scale score was negatively correlated with MFV at T15 (r = -0.825; p < 0.05).
conclusionThis pilot study showed a significant influence on cerebral blood flow velocity by TA. This study lays a foundation for larger-scale studies that may prove acupuncture to be a useful tool for cerebral blood flow enhancement during post-stroke rehabilitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.