Evidence map›Paper›PMID 26569474›Full record

ArticleNature materials2016

A magnetic protein biocompass.

Siying Qin, Hang Yin, Celi Yang, Yunfeng Dou, Zhongmin Liu, Peng Zhang, He Yu, Yulong Huang, Jing Feng, Junfeng Hao and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
40.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 352 citations in OpenAlex.

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  9. A hybrid compass mechanism combining radical pairs and magnetite crystals.Proceedings of the National Academy of Sciences of the United States of America · 2026
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73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Siying QinState Key Laboratory of Membrane Biology, Laboratory of Molecular Biophysics, School of Life Sciences, Peking University, Beijing 100871, China.
Hang YinState Key Laboratory of Membrane Biology, Laboratory of Molecular Biophysics, School of Life Sciences, Peking University, Beijing 100871, China.
Celi YangState Key Laboratory of Membrane Biology, Laboratory of Molecular Biophysics, School of Life Sciences, Peking University, Beijing 100871, China.
Yunfeng DouState Key Laboratory of Membrane Biology, Laboratory of Molecular Biophysics, School of Life Sciences, Peking University, Beijing 100871, China.
Zhongmin LiuMinistry of Education Key Laboratory of Protein Science, Center for Structural Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Peng ZhangKey Laboratory of Protein &Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
He YuSchool of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Yulong HuangInstitute of Physics and Beijing National Laboratory for Condensed Matter Physics, Chinese Academy of Sciences, Beijing 100190, China.
Jing FengKey Laboratory of Protein &Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Junfeng HaoCenter for Experimental Animal Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Jia HaoState Key Laboratory of Membrane Biology, Laboratory of Molecular Biophysics, School of Life Sciences, Peking University, Beijing 100871, China.
Lizong DengKey Laboratory of Protein &Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Xiyun YanKey Laboratory of Protein &Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Xiaoli DongInstitute of Physics and Beijing National Laboratory for Condensed Matter Physics, Chinese Academy of Sciences, Beijing 100190, China.
Zhongxian ZhaoInstitute of Physics and Beijing National Laboratory for Condensed Matter Physics, Chinese Academy of Sciences, Beijing 100190, China.
Taijiao JiangKey Laboratory of Protein &Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Hong-Wei WangMinistry of Education Key Laboratory of Protein Science, Center for Structural Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Shu-Jin LuoSchool of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Can XieState Key Laboratory of Membrane Biology, Laboratory of Molecular Biophysics, School of Life Sciences, Peking University, Beijing 100871, China.
State Key Laboratory of Membrane BiologyCenter for Life Sciences · CNChinese Academy of Sciences · CNInstitute of Biophysics · CNInstitute of Physics · CNPeking University · CNNational Laboratory for Superconductivity · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The notion that animals can detect the Earth's magnetic field was once ridiculed, but is now well established. Yet the biological nature of such magnetosensing phenomenon remains unknown. Here, we report a putative magnetic receptor (Drosophila CG8198, here named MagR) and a multimeric magnetosensing rod-like protein complex, identified by theoretical postulation and genome-wide screening, and validated with cellular, biochemical, structural and biophysical methods. The magnetosensing complex consists of the identified putative magnetoreceptor and known magnetoreception-related photoreceptor cryptochromes (Cry), has the attributes of both Cry- and iron-based systems, and exhibits spontaneous alignment in magnetic fields, including that of the Earth. Such a protein complex may form the basis of magnetoreception in animals, and may lead to applications across multiple fields.

Indexed as

MagneticsAnimalsAntibodiesBiocompatible MaterialsBiophysicsColumbidaeComputer SimulationDrosophila melanogasterGene Expression RegulationGenome-Wide Association StudyIron-Sulfur ProteinsMicroscopy, ElectronModels, MolecularMutagenesisProtein ConformationProtein TransportAntibodiesBiocompatible MaterialsIron-Sulfur ProteinsRNA, Messenger

Identifiers

PMID26569474
OpenAlexW2214913952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.