Evidence map›Paper›PMID 26569343›Full record

ReviewCurrent opinion in virology2015

Dissecting vectorial capacity for mosquito-borne viruses.

Laura D Kramer, Alexander T Ciota

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Transovarial transmission of mosquito-borne viruses: a systematic review.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Review
  9. Article
  10. Article
  11. Vector competence acrossJournal of virology · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Laura D KramerWadsworth Center, New York State Department of Health, and School of Public Health, State University of New York at Albany, Albany, NY, USA. Electronic address: laura.kramer@health.ny.gov.
Alexander T CiotaWadsworth Center, New York State Department of Health, and School of Public Health, State University of New York at Albany, Albany, NY, USA. Electronic address: alexander.ciota@health.ny.gov.

Funding

Training in Biodefense and Emerging Infectious DiseaseT32AI055429 · NIAID · WADSWORTH CENTER · PI MCDONOUGH, KATHLEEN A · 2004 to 2014
$2.2M
Genetic determinants of adaptation of two flavivirusesR01AI077669 · NIAID · WADSWORTH CENTER · PI KRAMER, LAURA D · 2009 to 2013
$1.8M
Mechanisms of West Nile virus selection and strain displacementR56AI069217 · NIAID · WADSWORTH CENTER · PI KRAMER, LAURA D · 2008 to 2009
$795k
US BASED COLLABORATION IN EMERGING VIRAL AND PRION DISEASES-266025490N01AI025490 · NIAID · HEALTH RESEARCH, INC. · 2003 to 2004
–
NIAID NIH HHS 1R01AI069217-01NIAID NIH HHS N01 AI025490NIAID NIH HHS R01 AI077669NIAID NIH HHS R01-AI-077669NIAID NIH HHS R56 AI069217NIAID NIH HHS T32 AI055429NIAID NIH HHS T32-AI055429-03
6 · The paper itself

Abstract

The inter-relationship between mosquitoes and the viruses they transmit is complex. While previously understood barriers to infection and transmission remain valid, additional factors have been uncovered that suggest an 'arms race' between mosquito and virus. These include the mosquito microbiota and interplay between mosquito and viral genetics. Following an infectious blood meal, the mosquito mounts an immune and transcriptional response, leading to altered expression of multiple genes. These complex interactions, specific to vector and virus genotypes, combine with external influences, particularly temperature, to determine vector competence. The mosquito's response to the infecting agent may have consequences in terms of longevity, feeding behavior and/or fecundity. These factors, together with population density and the frequency of host contact determine vectorial capacity.

Indexed as

Host-Pathogen InteractionsAnimalsCulicidaeGenetic VectorsHumansInsect VectorsMicrobial InteractionsMicrobiotaSpecies SpecificityViruses

Identifiers

PMID26569343
PMCPMC4688158

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.