ArticleCancers2015
Tumor Volumes and Prognosis in Laryngeal Cancer.
Article in Cancers, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- "Histologic type, treatment and prognosis of carcinomas of the larynx: A review".Virchows Archiv : an international journal of pathology · 2026Review
- Global, regional and country-specific burden of larynx cancer due to occupational exposure to asbestos: a systematic analysis of the Global Burden of Disease Study 2021.BMC public health · 2025Article
- Investigation of photothermal treatment with 532 nm laser light on laryngeal cancer in an in vivo tumor model.Lasers in medical science · 2024Article
- Electrochemotherapy for head and neck cancers: possibilities and limitations.Frontiers in oncology · 2024Review
- Treatment Results for Stage III Laryngeal Cancer: Analysis of a Populational Database Using Propensity Scores.International archives of otorhinolaryngology · 2022Article
- Automated segmentation of the larynx on computed tomography images: a review.Biomedical engineering letters · 2022Review
- Trend of the Burden of Larynx Cancer in Brazil, 1990 to 2019.Revista da Sociedade Brasileira de Medicina Tropical · 2022Article
- Prognostic value of the maximum standardized uptake value for the locoregional control in early glottic cancer.Radiation oncology journal · 2021Article
- PrognosiT: Pathway/gene set-based tumour volume prediction using multiple kernel learning.BMC bioinformatics · 2021Article
- Emerging Concepts and Novel Strategies in Radiation Therapy for Laryngeal Cancer Management.Cancers · 2020Review
- MicroRNA-107 inhibits proliferation and invasion of laryngeal squamous cell carcinoma cells by targeting CACNA2D1 in vitro.Anti-cancer drugs · 2020Article
- Updates on larynx cancer epidemiology.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2020Article
- The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx.BioMed research international · 2019Article
- Response assessment after induction chemotherapy for head and neck squamous cell carcinoma: From physical examination to modern imaging techniques and beyond.Head & neck · 2017Review
- Trans-oral miniature X-ray radiation delivery system with endoscopic optical feedback.International journal of computer assisted radiology and surgery · 2017Article
- Survival Rates Using Individualized Bioselection Treatment Methods in Patients With Advanced Laryngeal Cancer.JAMA otolaryngology-- head & neck surgery · 2017Article
- Article
- Influence of tumor topography on clinical-morphological profile of laryngeal malignancies.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Tumor staging systems for laryngeal cancer (LC) have been developed to assist in estimating prognosis after treatment and comparing treatment results across institutions. While the laryngeal TNM system has been shown to have prognostic information, varying cure rates in the literature have suggested concern about the accuracy and effectiveness of the T-classification in particular. To test the hypothesis that tumor volumes are more useful than T classification, we conducted a retrospective review of 78 patients with laryngeal cancer treated with radiation therapy at our institution. Using multivariable analysis, we demonstrate the significant prognostic value of anatomic volumes in patients with previously untreated laryngeal cancer. In this cohort, primary tumor volume (GTVP), composite nodal volumes (GTVN) and composite total volume (GTVP + GTVN = GTVC) had prognostic value in both univariate and multivariate cox model analysis. Interestingly, when anatomic volumes were measured from CT scans after a single cycle of induction chemotherapy, all significant prognosticating value for measured anatomic volumes was lost. Given the literature findings and the results of this study, the authors advocate the use of tumor anatomic volumes calculated from pretreatment scans to supplement the TNM staging system in subjects with untreated laryngeal cancer. The study found that tumor volume assessment after induction chemotherapy is not of prognostic significance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.