ArticleNature genetics2016
Domestication selected for deceleration of the circadian clock in cultivated tomato.
Article in Nature genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
93 citing papers in PubMed, 226 citations in OpenAlex.
- Genome evolution of Mediterranean olives following DNA repeats diversification.The plant genome · 2026Article
- SPIRAL: A versatile online single time-point circadian analysis platform for rice.Science advances · 2026Article
- A noncoding SNP in ELF3 alters ELF3β expression and confers adaptation of Arabidopsis to a continental climate.Plant physiology · 2026Article
- Time after time: a quarter century of progress in plant circadian biology.Npj biological timing and sleep · 2026Review
- Early birds and night owls: natural variation of circadian traits in plants.Journal of experimental botany · 2026Review
- What metabolomics has taught us about tomato fruit ripening and quality.Journal of experimental botany · 2025Review
- Breeding for delayed bolting decelerated the circadian clock in cultivated lettuce.The New phytologist · 2025Article
- Comparative transcriptomic and proteomic analyses of hypoxia response in wild and cultivated tomato roots.BMC genomics · 2025Article
- Abundant clock proteins point to missing molecular regulation in the plant circadian clock.Molecular systems biology · 2025Article
- Sensitivity to Photoperiod Is a Complex Trait inPlant direct · 2025Article
- BioClocks UK: driving robust cycles of discovery to impact.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Circannual Clock inPlants (Basel, Switzerland) · 2025Article
- The circadian clock participates in seasonal growth in Norway spruce (Picea abies).Tree physiology · 2024Article
- In vitro induction of tetraploids and their phenotypic and transcriptome analysis in Glehnia littoralis.BMC plant biology · 2024Article
- Circadian and photoperiodic regulation of the vegetative to reproductive transition in plants.Communications biology · 2024Review
- Evaluating the Adaptive Fitness of Circadian Clocks and their Evolution.Journal of biological rhythms · 2024Review
- Unlocking allelic variation in circadian clock genes to develop environmentally robust and productive crops.Planta · 2024Review
- early maturity 7 promotes early flowering by controlling the light input into the circadian clock in barley.Plant physiology · 2024Article
- Tomato and mini-cucumber tolerance to photoperiodic injury involves photorespiration and the engagement of nighttime cyclic electron flow from dynamic LEDs.Frontiers in plant science · 2024Article
- Multiple light signaling pathways control solar tracking in sunflowers.PLoS biology · 2023Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
13 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The circadian clock is a critical regulator of plant physiology and development, controlling key agricultural traits in crop plants. In addition, natural variation in circadian rhythms is important for local adaptation. However, quantitative modulation of circadian rhythms due to artificial selection has not yet been reported. Here we show that the circadian clock of cultivated tomato (Solanum lycopersicum) has slowed during domestication. Allelic variation of the tomato homolog of the Arabidopsis gene EID1 is responsible for a phase delay. Notably, the genomic region harboring EID1 shows signatures of a selective sweep. We find that the EID1 allele in cultivated tomatoes enhances plant performance specifically under long day photoperiods, suggesting that humans selected slower circadian rhythms to adapt the cultivated species to the long summer days it encountered as it was moved away from the equator.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.