ReviewWorld journal of virology2015
Hepatitis E virus infection: Epidemiology and treatment implications.
Review in World journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Review
- Treatment of Hepatitis E.Advances in experimental medicine and biology · 2023Article
- Research on a rat model of genotype IV swine hepatitis E virus.Veterinary medicine and science · 2022Article
- First Report of the HEV Seroprevalence and the Risk Factor Assessment in the West Bank, Palestine, during the Period of 2015-2017.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022Article
- Is There A Correlation Between COVID-19 and Hepatitis A and Hepatitis E Serum Antibody Level?Iranian journal of pathology · 2022Article
- Hepatitis E Virus in the Food of Animal Origin: A Review.Foodborne pathogens and disease · 2021Review
- Serological Survey on Bacterial and Viral Pathogens in Wild Boars Hunted in Tuscany.EcoHealth · 2020Article
- Viral Hepatitis E and Chronicity: A Growing Public Health Concern.Frontiers in microbiology · 2020Review
- Prevalence of hepatitis E virus in thalassemia patients with hepatitis C in Tehran, Iran.Iranian journal of microbiology · 2019Article
- Hepatitis E virus: advances and challenges.Nature reviews. Gastroenterology & hepatology · 2018Review
- Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review.BMC infectious diseases · 2018Review
- Article
- Development of new hepatitis E vaccines.Human vaccines & immunotherapeutics · 2018Review
- Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Detection and Characterization of Hepatitis E Virus in Goats at Slaughterhouse in Tai'an Region, China.BioMed research international · 2017Article
- Hepatitis E Virus in Wild Boars and Spillover Infection in Red and Roe Deer, Germany, 2013-2015.Emerging infectious diseases · 2017Article
- Guillain-Barré and Miller Fisher syndromes in patients with anti-hepatitis E virus antibody: a hospital-based survey in Japan.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2016Article
- Epidemiology of Hepatitis E in Pregnant Women and Children in Iran: A General Overview.Journal of clinical and translational hepatology · 2016Review
- Role of Envelopment in the HEV Life Cycle.Viruses · 2016Review
- Epidemiology of hepatitis E virus in Iran.World journal of gastroenterology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis E virus (HEV) infection is now established as an emerging enteric viral hepatitis. Standard treatments in acute and chronic hepatitis E remain to be established. This study undertakes a review of the epidemiology, treatment implication and vaccine prevention from published literature. HEV infection is a worldwide public health problem and can cause acute and chronic hepatitis E. HEV genotypes 1 and 2 are primarily found in developing countries due to waterborne transmission, while the zoonotic potential of genotypes 3 and 4 affects mostly industrialized countries. An awareness of HEV transmission through blood donation, especially in the immunocompromised and solid organ transplant patients, merits an effective anti-viral therapy. There are currently no clear indications for the treatment of acute hepatitis E. Despite concerns for side effects, ribavirin monotherapy or in combination with pegylated interferon alpha for at least 3 mo appeared to show significant efficacy in the treatment of chronic hepatitis E. However, there are no available treatment options for specific patient population groups, such as women who are pregnant. Vaccination and screening of HEV in blood donors are currently a global priority in managing infection. New strategies for the treatment and control of hepatitis E are required for both acute and chronic infections, such as prophylactic use of medications, controlling large outbreaks, and finding acceptable antiviral therapy for pregnant women and other patient groups for whom the current options of treatment are not viable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.