ArticleEvoDevo2015
Species-specific modifications of mandible shape reveal independent mechanisms for growth and initiation of the coronoid.
Article in EvoDevo, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease.Journal of anatomy · 2026Article
- Three-dimensional measurement of the coronoid process and structural consistency analysis in patients with long-face morphology.BMC oral health · 2025Article
- Do astigmatid teeth matter: a tribological review of cheliceral chelae in co-occuring mites from UK beehives.Experimental & applied acarology · 2024Review
- Spatial and Temporal Expression of Ectodysplasin-A Signaling Pathway Members During Mandibular Condylar Development in Postnatal Mice.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023Article
- Double mandible coronoid process: a very unusual feature.Surgical and radiologic anatomy : SRA · 2023Article
- Covariation of brain and skull shapes as a model to understand the role of crosstalk in development and evolution.Evolution & development · 2023Article
- Evolution and development of the mammalian jaw joint: Making a novel structure.Evolution & development · 2023Review
- Fgf8 dosage regulates jaw shape and symmetry through pharyngeal-cardiac tissue relationships.Developmental dynamics : an official publication of the American Association of Anatomists · 2022Article
- Two cases of bilateral coronoid process hyperplasia causing restricted mouth opening.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- Making and shaping endochondral and intramembranous bones.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Review
- Making a bat: The developmental basis of bat evolution.Genetics and molecular biology · 2021Article
- Article
- Association of Dysplastic Coronoid Process with Long-Face Morphology.Journal of dental research · 2020Article
- Article
- The TMJ Disc Is a Common Ancestral Feature in All Mammals, as Evidenced by the Presence of a Rudimentary Disc During Monotreme Development.Frontiers in cell and developmental biology · 2020Article
- Molecular and cellular mechanisms underlying the evolution of form and function in the amniote jaw.EvoDevo · 2019Review
- FGF and TGFβ signaling link form and function during jaw development and evolution.Developmental biology · 2018Article
- Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups.Journal of clinical medicine · 2018Article
- Bilateral coronoid hyperplasia causing painless limitation of mandibular movement.Radiology case reports · 2018Article
- Major evolutionary transitions and innovations: the tympanic middle ear.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe variation in mandibular morphology of mammals reflects specialisations for different diets. Omnivorous and carnivorous mammals posses large mandibular coronoid processes, while herbivorous mammals have proportionally smaller or absent coronoids. This is correlated with the relative size of the temporalis muscle that forms an attachment to the coronoid process. The role of this muscle attachment in the development of the variation of the coronoid is unclear.
resultsBy comparative developmental biology and mouse knockout studies, we demonstrate here that the initiation and growth of the coronoid are two independent processes, with initiation being intrinsic to the ossifying bone and growth dependent upon the extrinsic effect of muscle attachment. A necessary component of the intrinsic patterning is identified as the paired domain transcription factor Pax9. We also demonstrate that Sox9 plays a role independent of chondrogenesis in the growth of the coronoid process in response to muscle interaction.
conclusionsThe mandibular coronoid process is initiated by intrinsic factors, but later growth is dependent on extrinsic signals from the muscle. These extrinsic influences are hypothesised to be the basis of the variation in coronoid length seen across the mammalian lineage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.