Evidence map›Paper›PMID 26568787›Full record

ArticleJournal of coatings technology and research2015

Encapsulation of Volatile Compounds in Silk Microparticles.

Roberto Elia, Jin Guo, Stephanie Budijono, Valery Normand, Daniel Benczédi, Fiorenzo Omenetto, David L Kaplan

Abstract read
In one paragraph

Article in Journal of coatings technology and research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Controlled-ReleaseClinical, cosmetic and investigational dermatology · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roberto EliaDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155.
Jin GuoDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155.
Stephanie BudijonoFirmenich Inc., Plainsboro, New Jersey 08536.
Valery NormandFirmenich Inc., Plainsboro, New Jersey 08536.
Daniel BenczédiFirmenich SA, 1, Route des Jeunes, 1211 Geneva 8, Switzerland.
Fiorenzo OmenettoDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155.
David L KaplanDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155.

Funding

Translational Bioreactors - Engineering Complex TissuesP41EB002520 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2004 to 2018
$16.7M
NIBIB NIH HHS P41 EB002520
6 · The paper itself

Abstract

Various techniques have been employed to entrap fragrant oils within microcapsules or microparticles in the food, pharmaceutical, and chemical industries for improved stability and delivery. In the present work we describe the use of silk protein microparticles for encapsulating fragrant oils using ambient processing conditions to form an all-natural biocompatible matrix. These microparticles are stabilized via physical crosslinking, requiring no chemical agents, and are prepared with aqueous and ambient processing conditions using polyvinyl alcohol-silk emulsions. The particles were loaded with fragrant oils via direct immersion of the silk particles within an oil bath. The oil-containing microparticles were coated using alternating silk and polyethylene oxide layers to control the release of the oil from the microspheres. Particle morphology and size, oil loading capacity, release rates as well as silk-oil interactions and coating treatments were characterized. Thermal analysis demonstrated that the silk coatings can be tuned to alter both retention and release profiles of the encapsulated fragrance. These oil containing particles demonstrate the ability to adsorb and controllably release oils, suggesting a range of potential applications including cosmetic and fragrance utility.

Indexed as

coatingscontrolled releaseemulsionmicroencapsulationsilk fibroinstabilization

Identifiers

PMID26568787
PMCPMC4640459

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.