ReviewJournal of experimental neuroscience2015
Adult Astrogenesis and the Etiology of Cortical Neurodegeneration.
Review in Journal of experimental neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Astrocytes from P301S Tau mice exhibit non-canonical protein secretion and reduced morphological complexity.Neural regeneration research · 2026Article
- Brain stars take the lead during critical periods of early postnatal brain development: relevance of astrocytes in health and mental disorders.Molecular psychiatry · 2024Review
- Astrocyte-Neuron Interaction via the Glutamate-Glutamine Cycle and Its Dysfunction in Tau-Dependent Neurodegeneration.International journal of molecular sciences · 2024Review
- The Synucleins and the Astrocyte.Biology · 2023Review
- Interactions between Major Bioactive Polyphenols of Sugarcane Top: Effects on Human Neural Stem Cell Differentiation and Astrocytic Maturation.International journal of molecular sciences · 2022Article
- Dysfunctional glia: contributors to neurodegenerative disorders.Neural regeneration research · 2021Review
- The Astrogenic Balance in the Aging Brain.Current neuropharmacology · 2021Review
- Glial cells in Parkinson´s disease: protective or deleterious?Cellular and molecular life sciences : CMLS · 2020Review
- Defining a Time Window for Neuroprotection and Glia Modulation by Caffeine After Neonatal Hypoxia-Ischaemia.Molecular neurobiology · 2020Article
- Inhibition of GSK3β and RIP1K Attenuates Glial Scar Formation Induced by Ischemic StrokeFrontiers in pharmacology · 2020Article
- Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems.Scientific reports · 2019Article
- Inflammatory Response in the CNS: Friend or Foe?Molecular neurobiology · 2017Review
- Astrocytes in mouse models of tauopathies acquire early deficits and lose neurosupportive functions.Acta neuropathologica communications · 2017Article
- Concordance of Several Subcellular Interactions Initiates Alzheimer's Dementia: Their Reversal Requires Combination Treatment.American journal of Alzheimer's disease and other dementias · 2017Review
- AstrogenesisNeural regeneration research · 2017Article
- Natural product HTP screening for attenuation of cytokine-induced neutrophil chemo attractants (CINCs) and NO2- in LPS/IFNγ activated glioma cells.Journal of neuroimmunology · 2017Article
- The Role of Astrocytes in Neuroprotection after Brain Stroke: Potential in Cell Therapy.Frontiers in molecular neuroscience · 2017Review
- Cocaine promotes primary human astrocyte proliferation via JNK-dependent up-regulation of cyclin A2.Restorative neurology and neuroscience · 2016Article
- Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus.Molecular brain · 2016Article
- Altered Morphologies and Functions of the Olfactory Bulb and Hippocampus Induced by miR-30c.Frontiers in neuroscience · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As more evidence points to a clear role for astrocytes in synaptic processing, synaptogenesis and cognition, continuing research on astrocytic function could lead to strategies for neurodegenerative disease prevention. Reactive astrogliosis results in astrocyte proliferation early in injury and disease states and is considered neuroprotective, indicating a role for astrocytes in disease etiology. This review describes the different types of human cortical astrocytes and the current evidence regarding adult cortical astrogenesis in injury and degenerative disease. A role for disrupted astrogenesis as a cause of cortical degeneration, with a focus on the tauopathies and synucleinopathies, will also be considered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.