ArticleMechanics of materials : an international journal2016
Indentation Analysis of Biphasic Viscoelastic Hydrogels.
Article in Mechanics of materials : an international journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Material properties in regenerating axolotl limbs using inverse finite element analysis.Journal of the mechanical behavior of biomedical materials · 2024Article
- Green and Integrated Wearable Electrochemical Sensor for Chloride Detection in Sweat.Sensors (Basel, Switzerland) · 2022Article
- Hydrogel scaffolds based on blood plasma cryoprecipitate and collagen derived from various sources: Structural, mechanical and biological characteristics.Bioactive materials · 2019Article
- Automated In Vivo Sub-Hertz Analysis of Viscoelasticity (SAVE) for Evaluation of Breast Lesions.IEEE transactions on bio-medical engineering · 2018Article
- Viscoelastic properties of human pancreatic tumors and in vitro constructs to mimic mechanical properties.Acta biomaterialia · 2018Article
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Authors and funding
4 authors.
Funding
Abstract
Mechanical properties of soft biological materials are dependent on the responses of the two phases of which they are comprised: the solid matrix and interstitial fluid. Indentation techniques are commonly used to measure properties of such materials, but comparisons between different experimental and analytical techniques can be difficult. Most models relating load and time during spherical indentation are based on Hertzian contact theory, but the exact limitation of this theory for soft materials are unclear. Here, we examine the response of gelatin hydrogels to shear and indentation loading to quantify combined effects of the solid and fluid phases. The instantaneous behavior of the hydrogels is different for each test geometry and loading rate, but the relaxed response, measured by the relaxed modulus, is the same for all tests, within 17%. Additionally, indentation depths from 15-25% of the radius of the spherical indenter are found to minimize error in the estimate of relaxed modulus.
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