ArticleGenome biology and evolution2015
Parallel Selection Revealed by Population Sequencing in Chicken.
Article in Genome biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Kinglet in the Poultry Court of Russia: Whole-Genome Insights into Ancestry, Genetic Variability, Selection Footprints and Candidate Genes in a Unique Local Chicken Breed Relative to Other Bantam/Dwarf Breeds.Animals : an open access journal from MDPI · 2026Article
- Large-scale genome-wide SNP analysis reveals the rugged (and ragged) landscape of global ancestry, phylogeny, and demographic history in chicken breeds.Journal of Zhejiang University. Science. B · 2024Article
- Whole genome analyses reveal novel genes associated with chicken adaptation to tropical and frigid environments.Journal of advanced research · 2023Article
- Systematic Selection Signature Analysis of Chinese Gamecocks Based on Genomic and Transcriptomic Data.International journal of molecular sciences · 2023Article
- Assessment the effect of genomic selection and detection of selective signature in broilers.Poultry science · 2022Article
- Article
- How imputation can mitigate SNP ascertainment Bias.BMC genomics · 2021Article
- Article
- The DomesticGenetics · 2019Article
- Polygenic Basis and Variable Genetic Architectures Contribute to the Complex Nature of Body Weight -A Genome-Wide Study in Four Chinese Indigenous Chicken Breeds.Frontiers in genetics · 2018Article
- Article
- Whole-genome resequencing reveals candidate mutations for pig prolificacy.Proceedings. Biological sciences · 2017Article
- Genetic Mapping of Quantitative Trait Loci for Egg Production and Egg Quality Traits in Chickens: a Review.The journal of poultry science · 2017Review
- A New Chicken Genome Assembly Provides Insight into Avian Genome Structure.G3 (Bethesda, Md.) · 2017Article
- Genomic analysis of Ugandan and Rwandan chicken ecotypes using a 600 k genotyping array.BMC genomics · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human-driven selection during domestication and subsequent breed formation has likely left detectable signatures within the genome of modern chicken. The elucidation of these signatures of selection is of interest from the perspective of evolutionary biology, and for identifying genes relevant to domestication and improvement that ultimately may help to further genetically improve this economically important animal. We used whole genome sequence data from 50 hens of commercial white (WL) and brown (BL) egg-laying chicken along with pool sequences of three meat-type chicken to perform a systematic screening of past selection in modern chicken. Evidence of positive selection was investigated in two steps. First, we explored evidence of parallel fixation in regions with overlapping elevated allele frequencies in replicated populations of layers and broilers, suggestive of selection during domestication or preimprovement ages. We confirmed parallel fixation in BCDO2 and TSHR genes and found four candidates including AGTR2, a gene heavily involved in "Ascites" in commercial birds. Next, we explored differentiated loci between layers and broilers suggestive of selection during improvement in chicken. This analysis revealed evidence of parallel differentiation in genes relevant to appearance and production traits exemplified with the candidate gene OPG, implicated in Osteoporosis, a disorder related to overconsumption of calcium in egg-laying hens. Our results illustrate the potential for population genetic techniques to identify genomic regions relevant to the phenotypes of importance to breeders.
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