Evidence map›Paper›PMID 26568122›Full record

ReviewSleep medicine clinics2015

Consequences of Circadian Disruption on Cardiometabolic Health.

Sirimon Reutrakul, Kristen L Knutson

Abstract readReview
In one paragraph

Review in Sleep medicine clinics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Within-Person Seasonal Variability of Aminotransferases and Long-Term Glycemic Control in Adults With Type 2 Diabetes (JDDM 85).Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Fluctuations in Sleep Duration and Timing and Cardiometabolic Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Circadian nutrition and obesity: timing as a nutritional strategy.Journal of health, population, and nutrition · 2025
    Review
  15. Circadian rhythms in cardiovascular disease.European heart journal · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sirimon ReutrakulDivision of Endocrinology and Metabolism, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Bangkok 10400, Thailand.
Kristen L KnutsonSection of Pulmonary and Critical Care, Department of Medicine, University of Chicago, 5841 South Maryland Avenue, MC 6076, Chicago, IL 60637, USA. Electronic address: kknutson@medicine.bsd.uchicago.edu.

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Home sleep and circadian phase: mediators of racial disparities in diabetes riskR01DK095207 · NIDDK · UNIVERSITY OF CHICAGO · PI KNUTSON, KRISTEN · 2012 to 2016
$2.1M
NCATS NIH HHS UL1 TR000430NIDDK NIH HHS R01 DK095207
6 · The paper itself

Abstract

Cardiovascular disease, diabetes and obesity are highly prevalent diseases associated with reduced quality of life and life expectancy. We discuss a novel risk factor for these cardiometabolic diseases: circadian disruption. Circadian disruption occurs when the internal circadian (∼24-hour) rhythms are not in synchrony with the environment or each other. This paper reviews (1) cardiometabolic health of shift work, which often leads to circadian disruption, (2) effects of experimentally disrupted circadian rhythms on cardiometabolic function, (3) observational studies of sleep timing and behavioral chronotype, and (4) potential mediators linking chronotype and shift work to circadian disruption and cardiometabolic health.

Indexed as

Cardiovascular DiseasesCircadian RhythmHumansCardiovascular diseaseCircadian rhythmsDiabetesShift work

Identifiers

PMID26568122
PMCPMC4648711

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.