Evidence map›Paper›PMID 26567611›Full record

ReviewExpert review of anticancer therapy2016

Current status and future perspectives of fluorescence-guided surgery for cancer.

Jonathan C DeLong, Robert M Hoffman, Michael Bouvet

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Expert review of anticancer therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  11. Targeted Optical Imaging of the Glucagonlike Peptide 1 Receptor Using Exendin-4-IRDye 800CW.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonathan C DeLonga Department of Surgery , University of California San Diego , San Diego , CA , USA.
Robert M Hoffmana Department of Surgery , University of California San Diego , San Diego , CA , USA.
Michael Bouveta Department of Surgery , University of California San Diego , San Diego , CA , USA.

Funding

Fluorophore-Conjugated Antibodies for Imaging and Resection of GI TumorsR01CA142669 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOUVET, MICHAEL, YANG, MENG · 2010 to 2015
$1.7M
Color-Coded Imaging of Pancreatic Cancer Microenvironment for Drug DiscoveryR01CA132971 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOUVET, MICHAEL, YANG, MENG · 2009 to 2013
$1.7M
NCI NIH HHS CA132971NCI NIH HHS CA142669NCI NIH HHS R01 CA132971NCI NIH HHS R01 CA142669
6 · The paper itself

Abstract

Curative cancer surgery is dependent on the removal of all primary tumor and metastatic cancer cells. Preoperative imaging, intraoperative inspection and palpation, as well as pathological margin confirmation aid the surgeon, but these methods are lacking in sensitivity and can be highly subjective. Techniques in fluorescence-guided surgery (FGS) are emerging that selectively illuminate cancer cells, enhancing the distinction between tumors and surrounding tissues with the potential for single-cell sensitivity. FGS enhances tumor detection, surgical navigation, margin confirmation, and in some cases can be combined with therapeutic techniques to eliminate microscopic disease. In this review, we describe the preclinical developments and currently-used techniques for FGS.

Indexed as

FluorescenceAnimalsFluorescent DyesHumansNeoplasmsSensitivity and SpecificityFluorescent DyesFluorescence-guided surgery (FGS)fluorescent proteinsfluorophorephotoimmunotherapytheranostics

Identifiers

PMID26567611
PMCPMC5572645

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.