Evidence map›Paper›PMID 26567370›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2015

Risk Factors for Infection-Related Hospitalization in In-Center Hemodialysis.

Lorien S Dalrymple, Yi Mu, Danh V Nguyen, Patrick S Romano, Glenn M Chertow, Barbara Grimes, George A Kaysen, Kirsten L Johansen

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Community Racial Composition and Hospitalization Among Patients Receiving In-Center Hemodialysis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Article
  16. Review
  17. COVID-19, Low-Molecular-Weight Heparin, and Hemodialysis.Kidney & blood pressure research · 2020
    Article
  18. Article
  19. Article
  20. Arteriovenous Fistula Maturation in Prevalent Hemodialysis Patients in the United States: A National Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Lorien S DalrympleDepartments of Medicine and ldalrymple@ucdavis.edu.
Yi MuHealth Sciences, University of California, Davis, California;
Danh V NguyenDepartment of Medicine, University of California, Irvine, California;
Patrick S RomanoDepartments of Medicine and.
Glenn M ChertowDepartment of Medicine, Stanford University School of Medicine, Palo Alto, California;
Barbara GrimesDepartments of Epidemiology and Biostatistics and.
George A KaysenDepartments of Medicine and.
Kirsten L JohansenDepartments of Epidemiology and Biostatistics and Nephrology Section San Francisco Department of Veterans Affairs Medical Center, San Francisco, California Medicine, University of California, San Francisco, California; and.
Cancer Research And Biostatistics · USSan Francisco VA Medical Center · USStanford University · USUniversity of California, Davis · USUniversity of California, Irvine · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR000002 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2012 to 2015
$12.2M
Institute for Clinical and Translational ScienceUL1TR000153 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2012 to 2015
$12.1M
Multilevel Time-Dynamic Modeling of Hospitalization and Survival in Patients on DialysisR01DK092232 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURUM, ESRA, NGUYEN, DANH V · 2011 to 2025
$4.9M
Prevalence and Impact of Frailty among Dialysis PatientsK24DK085153 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHANSEN, KIRSTEN L. · 2010 to 2021
$1.5M
Mentoring Patient-Oriented Clinical Investigators in NephrologyK24DK085446 · NIDDK · STANFORD UNIVERSITY · PI CHERTOW, GLENN MATTHEW · 2010 to 2022
$1.4M
Infection in Dialysis Patients: Risk Factors and OutcomesK23DK093584 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DALRYMPLE, LORIEN SKY · 2012 to 2014
$447k
NCATS NIH HHS UL1 TR000002NCATS NIH HHS UL1TR000002NCATS NIH HHS UL1 TR000153NCATS NIH HHS UL1TR000153NIDDK NIH HHS K23 DK093584NIDDK NIH HHS K24 DK085153NIDDK NIH HHS K24 DK085446NIDDK NIH HHS R01 DK092232
6 · The paper itself

Abstract

BACKGROUND AND

objectivesInfection-related hospitalizations have increased dramatically over the last 10 years in patients receiving in-center hemodialysis. Patient and dialysis facility characteristics associated with the rate of infection-related hospitalization were examined, with consideration of the region of care, rural-urban residence, and socioeconomic status. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The US Renal Data System linked to the American Community Survey and Rural-Urban Commuting Area codes was used to examine factors associated with hospitalization for infection among Medicare beneficiaries starting in-center hemodialysis between 2005 and 2008. A Poisson mixed effects model was used to examine the associations among patient and dialysis facility characteristics and the rate of infection-related hospitalization.

resultsAmong 135,545 Medicare beneficiaries, 38,475 (28%) had at least one infection-related hospitalization. The overall rate of infection-related hospitalization was 40.2 per 100 person-years. Age ≥ 85 years old, cancer, chronic obstructive pulmonary disease, inability to ambulate or transfer, drug dependence, residence in a care facility, serum albumin <3.5 g/dl at dialysis initiation, and dialysis initiation with an access other than a fistula were associated with a ≥ 20% increase in the rate of infection-related hospitalization. Patients residing in isolated small rural compared with urban areas had lower rates of hospitalization for infection (rate ratio, 0.91; 95% confidence interval, 0.86 to 0.97), and rates of hospitalization for infection varied across the ESRD networks. Measures of socioeconomic status (at the zip code level), total facility staffing, and the composition of staff (percentage of nurses) were not associated with the rate of hospitalization for infection.

conclusionsPatient and facility factors associated with higher rates of infection-related hospitalization were identified. The findings from this study can be used to identify patients at higher risk for infection and inform the design of infection prevention strategies.

Indexed as

Ambulatory Care FacilitiesHospitalizationAdolescentAdultAgedAged, 80 and overAge FactorsComorbidityCross InfectionFemaleHumansKidney Failure, ChronicMaleMedicareMiddle AgedRenal Dialysisend-stage renal diseaseepidemiology and outcomeshemodialysishospitalizationhumanskidney failure, chronicrenal dialysisrisk factorsserum albuminsocial class

Identifiers

PMID26567370
PMCPMC4670763
OpenAlexW2173582494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.