Evidence map›Paper›PMID 26567329›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2016

Classification of radiology reports for falls in an HIV study cohort.

Jonathan Bates, Samah J Fodeh, Cynthia A Brandt, Julie A Womack

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. The use of natural language processing in detecting and predicting falls within the healthcare setting: a systematic review.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Gerontologic Biostatistics and Data Science: Aging Research in the Era of Big Data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Robust clinical marker identification for diabetic kidney disease with ensemble feature selection.Journal of the American Medical Informatics Association : JAMIA · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan BatesYale School of Medicine, New Haven, CT VA Connecticut Healthcare System, West Haven, CT jonathan.bates@yale.edu.
Samah J FodehYale School of Medicine, New Haven, CT.
Cynthia A BrandtYale School of Medicine, New Haven, CT VA Connecticut Healthcare System, West Haven, CT.
Julie A WomackYale School of Nursing, West Haven, CT VA Connecticut Healthcare System, West Haven, CT.

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
MEDICAL INFORMATICS RESEARCH TRAINING AT YALET15LM007056 · NLM · YALE UNIVERSITY · PI Mark Bender Gerstein, LUCILA OHNO-MACHADO · 1987 to 2026
$22.2M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
Translational Research on Alcohol, Immunodeficiency, and Aging In COMpAAASU24AA022001 · NIAAA · YALE UNIVERSITY · PI BRANDT, CYNTHIA A. · 2012 to 2020
$3.2M
HIV Infection and Falls: Epidemiology and Risk AssessmentK01NR013437 · NINR · YALE UNIVERSITY · PI WOMACK, JULIE A · 2012 to 2014
$277k
NCRR NIH HHS UL1 RR024139NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U10 AA013566NIAAA NIH HHS U24 AA020794NIAAA NIH HHS U24 AA022001NINR NIH HHS K01 NR013437NLM NIH HHS 5 T15 LM007056
6 · The paper itself

Abstract

objectiveTo identify patients in a human immunodeficiency virus (HIV) study cohort who have fallen by applying supervised machine learning methods to radiology reports of the cohort.

methodsWe used the Veterans Aging Cohort Study Virtual Cohort (VACS-VC), an electronic health record-based cohort of 146 530 veterans for whom radiology reports were available (N=2 977 739). We created a reference standard of radiology reports, represented each report by a feature set of words and Unified Medical Language System concepts, and then developed several support vector machine (SVM) classifiers for falls. We compared mutual information (MI) ranking and embedded feature selection approaches. The SVM classifier with MI feature selection was chosen to classify all radiology reports in VACS-VC.

resultsOur SVM classifier with MI feature selection achieved an area under the curve score of 97.04 on the test set. When applied to all the radiology reports in VACS-VC, 80 416 of these reports were classified as positive for a fall. Of these, 11 484 were associated with a fall-related external cause of injury code (E-code) and 68 932 were not, corresponding to 29 280 patients with potential fall-related injuries who could not have been found using E-codes. DISCUSSION: Feature selection was crucial to improving the classifier's performance. Feature selection with MI allowed us to select the number of discriminative features to use for classification, in contrast to the embedded feature selection method, in which the number of features is chosen automatically.

conclusionMachine learning is an effective method of identifying patients who have suffered a fall. The development of this classifier supplements the clinical researcher's toolkit and reduces dependence on under-coded structured electronic health record data.

Indexed as

Accidental FallsSupport Vector MachineArea Under CurveCohort StudiesElectronic Health RecordsHIV InfectionsHumansRadiology Information SystemsUnified Medical Language SystemUnited StatesUnited States Department of Veterans AffairsVeteransagingfallsHIVinformation retrievaltext mining

Identifiers

PMID26567329
PMCPMC4954638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.