Evidence map›Paper›PMID 26567198›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2015

Effect of nutritional status and dietary patterns on human serum C-reactive protein and interleukin-6 concentrations.

Angelika Smidowicz, Julita Regula

Abstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  12. Nutritional strategies in kidney transplantation: optimising outcomes beyond surgery.Transplant international : official journal of the European Society for Organ Transplantation · 2026
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Angelika SmidowiczDepartment of Human Nutrition and Hygiene, Poznan University of Life Sciences, Poznan, Poland angelika.smidowicz@up.poznan.pl.ORCID http://orcid.org/0000-0001-6945-6004
Julita RegulaDepartment of Human Nutrition and Hygiene, Poznan University of Life Sciences, Poznan, Poland.ORCID http://orcid.org/0000-0002-3265-547X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inflammatory process plays an important role in the pathogenesis of many chronic diseases, such as cardiovascular diseases, diabetes mellitus type 2, and metabolic syndrome. Serum C-reactive protein (CRP) and interleukin-6 (IL-6) are widely tested inflammatory markers involved in the development of these diseases. Several studies indicate a relation between nutritional status and the concentrations of human high-sensitivity CRP and IL-6. Similarly, the role of diet in reducing inflammation and thereby modulating the risk of non-communicable diseases is supported by numerous studies. This review focuses on the effects of the selected nutrition models in humans on the concentrations of CRP and IL-6. It seems that the Mediterranean diet model is most effective in inhibiting inflammation. The Dietary Approaches to Stop Hypertension model and the plant nutrition model also have proven to be beneficial. The data on low-fat and low-carbohydrate diets are inconclusive. Comprehensive studies are necessary, taking into account the cumulative effect of dietary and other factors on the inflammatory process.

Indexed as

DietAdultAgedBiomarkersC-Reactive ProteinDiet, Carbohydrate-RestrictedDiet, Fat-RestrictedDiet, MediterraneanExerciseFemaleHumansHypertensionInflammationInterleukin-6MaleMEDLINEBiomarkersC-Reactive ProteinInterleukin-6DASH dietinflammationinflammatory markersMediterranean dietnutrition model

Identifiers

PMID26567198
PMCPMC4642421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.