Evidence map›Paper›PMID 26567088›Full record

ReviewAddiction (Abingdon, England)2016

Respiratory sinus arrhythmia as a potential measure in substance use treatment--outcome studies.

C J Price, S E Crowell

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01960036 (Body-oriented Therapy for Womens Substance Use Disorder Treatment), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01960036 nacompletednot on this map

Body-oriented Therapy for Womens Substance Use Disorder Treatment

TypeinterventionalSponsorUniversity of WashingtonRan2014 to 2018Enrolled217ConditionsSubstance Use DisorderArmsMindful Awareness in Body-oriented Therapy, Womens Health Education
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Vasomotor symptoms of menopause, sympathetic activity, and blood pressure in postmenopausal females.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  5. Review
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  10. Review
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  13. Improvement in women's cardiovascular functioning during cognitive-behavioral therapy for alcohol use disorder.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

C J PriceBiobehavioral Nursing, University of Washington, Seattle, WA, USA.
S E CrowellDepartment of Psychology, University of Utah, Salt Lake City, UT, USA.
Neurobehavioral Systems · USUniversity of Utah · US

Funding

Body-oriented Therapy for Womens Substance Use Disorder TreatmentR01DA033324 · NIDA · UNIVERSITY OF WASHINGTON · PI PRICE, CYNTHIA J · 2013 to 2016
$1.7M
NIDA NIH HHS R01 DA033324NIDA NIH HHS R01DA033324
6 · The paper itself

Abstract

BACKGROUND AND

aimsDysfunction of physiological regulation systems may underlie the disrupted emotional and self-regulatory processes among people with substance use disorder (SUD). This paper reviews evidence as to whether or not respiratory sinus arrhythmia (RSA), as a psychophysiological index of emotional regulation, could provide useful information in treatment-outcome research to provide insights into recovery processes.

methodsWe reviewed the use of RSA in clinical research and studies on SUD treatment. Search terms for the review of RSA in clinical research included respiratory sinus arrhythmia, heart rate variability, vagal, cardiac vagal control, psychophysiology, intervention, treatment, mindfulness, mind-body, mental health, substance use, chemical dependence, regulation and emotion regulation. For the review of RSA in intervention studies, we included only those that provided adequate description of psychophysiological methods, and examined RSA in the context of an intervention study.

resultsRSA appears to be able to provide an index of self-regulatory capacity; however, it has been little used in either intervention or treatment research. Of the four intervention studies included in this review, all were mindfulness-based interventions. Two studies were with substance-using samples, and both showed pre-post increases in RSA and related improved substance use outcomes. Two of the three studies were randomized controlled trials (RCTs), and both showed significant increases in RSA in the experimental compared to comparison condition.

conclusionRespiratory sinus arrhythmia may be a useful index of emotional regulation in people with substance use disorder, and a potential measure of underlying mechanisms for SUD treatment studies, particularly mindfulness-based interventions.

Indexed as

HumansOutcome Assessment, Health CareRespiratory Sinus ArrhythmiaSubstance-Related DisordersEmotion regulationinteroceptionmindfulnesspsychophysiologyrespiratory sinus arrhythmiasubstance use

Identifiers

PMID26567088
PMCPMC4801752
OpenAlexW2177399292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.