SynthesisActa neurochirurgica2016
Glioma surgery in eloquent areas: can we preserve cognition?
Synthesis in Acta neurochirurgica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- EANS-EANO guidelines on the extent of resection in gliomas.Neuro-oncology · 2026Guideline
- Metabolic Imaging as Future Technology and Innovation in Brain-Tumour Surgery: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Pooled it
- Effects of surgery on neurocognitive function in patients with glioma: a meta-analysis of immediate post-operative and long-term follow-up neurocognitive outcomes.Journal of neuro-oncology · 2019Pooled it
- The BLTT (Bonn Leistungs Tracking Test) in Patients with Temporal Lobe Gliomas-Feasibility of a Novel Neurocognitive Test Battery.NeuroSci · 2026Article
- Language Processing in Posterior Fossa Tumour Patients: Psycholinguistic Insights into the Word-Finding Ability.Cerebellum (London, England) · 2026Article
- The neuropsychological outcome of patients undergoing intraoperative MRI surgery for insular infiltrating gliomas.Journal of neuro-oncology · 2026Article
- How well can simple clinical features predict long-term language recovery after left-hemisphere glioma surgery?Journal of neuro-oncology · 2025Article
- Radiological and Not Clinical Variables Guide the Surgical Plan in Patients with Glioblastoma.Current oncology (Toronto, Ont.) · 2024Article
- What is the cognitive footprint of insular glioma?Frontiers in human neuroscience · 2024Review
- Preoperative subjective impairments in language and memory in brain tumor patients.Frontiers in oncology · 2024Article
- Review
- Continuous Real-Time Neuropsychological Testing during Resection Phase in Left and Right Prefrontal Brain Tumors.Current oncology (Toronto, Ont.) · 2023Article
- Radiotherapy-Induced Neurocognitive Dysfunction in Brain Tumor Survivors: Burden and Rehabilitation.Acta neurochirurgica. Supplement · 2023Article
- Long-Term Seizure Outcomes and Predictors in Patients with Dysembryoplastic Neuroepithelial Tumors Associated with Epilepsy.Brain sciences · 2022Article
- Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma.Scientific reports · 2022Article
- Review
- The Aftercare Survey: Assessment and intervention practices after brain tumor surgery in Europe.Neuro-oncology practice · 2022Article
- Assessment of neuropsychological function in brain tumor treatment: a comparison of traditional neuropsychological assessment with app-based cognitive screening.Acta neurochirurgica · 2022Article
- Neurocognitive Outcome and Seizure Freedom After Awake Surgery of Gliomas.Frontiers in oncology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCognitive preservation is crucial in glioma surgery, as it is an important aspect of daily life functioning. Several studies claimed that surgery in eloquent areas is possible without causing severe cognitive damage. However, this conclusion was relatively ungrounded due to the lack of extensive neuropsychological testing in homogenous patient groups. In this study, we aimed to elucidate the short-term and long-term effects of glioma surgery on cognition by identifying all studies who conducted neuropsychological tests preoperatively and postoperatively in glioma patients.
methodsWe systematically searched the electronical databases Embase, Medline OvidSP, Web of Science, PsychINFO OvidSP, PubMed, Cochrane, Google Scholar, Scirius and Proquest aimed at cognitive performance in glioma patients preoperatively and postoperatively.
resultsWe included 17 studies with tests assessing the cognitive domains: language, memory, attention, executive functions and/or visuospatial abilities. Language was the domain most frequently examined. Immediately postoperatively, all studies except one, found deterioration in one or more cognitive domains. In the longer term (3-6/6-12 months postoperatively), the following tests showed both recovery and deterioration compared with the preoperative level: naming and verbal fluency (language), verbal word learning (memory) and Trailmaking B (executive functions).
conclusionsCognitive recovery to the preoperative level after surgery is possible to a certain extent; however, the results are too arbitrary to draw definite conclusions and not all studies investigated all cognitive domains. More studies with longer postoperative follow-up with tests for cognitive change are necessary for a better understanding of the conclusive effects of glioma surgery on cognition.
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