Evidence map›Paper›PMID 26566539›Full record

ArticleOpen forum infectious diseases2015

Malignancies, Particularly B-Cell Lymphomas, Are a Frequent Cause of Mortality in Human Immunodeficiency Virus-1 Patients Despite Highly Active Antiretroviral Therapy.

Daniel O Griffin, Michael Metzger, Kaitlin Poeth, Kathy Deng, Arif Dharsee, Juan Carlos Rico, Joseph McGowan

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Daniel O GriffinDepartment of Biochemistry and Molecular Biophysics ; Department of Medicine, Division of Infectious Diseases , Columbia University Medical Center ; Department of Medicine-Division of Infectious Disease , Hofstra North Shore-LIJ School of Medicine , Manhasset.
Michael MetzgerDepartment of Biochemistry and Molecular Biophysics , Howard Hughes Medical Institute, Columbia University Medical Center , New York, New York.
Kaitlin PoethDepartment of Medicine-Division of Infectious Disease , Hofstra North Shore-LIJ School of Medicine , Manhasset.
Kathy DengDepartment of Medicine-Division of Infectious Disease , Hofstra North Shore-LIJ School of Medicine , Manhasset.
Arif DharseeDepartment of Medicine-Division of Infectious Disease , Hofstra North Shore-LIJ School of Medicine , Manhasset.
Juan Carlos RicoDepartment of Medicine-Division of Infectious Disease , Hofstra North Shore-LIJ School of Medicine , Manhasset.
Joseph McGowanDepartment of Biochemistry and Molecular Biophysics , Howard Hughes Medical Institute, Columbia University Medical Center , New York, New York.
Hofstra University · USColumbia University Irving Medical Center · USHoward Hughes Medical Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human immunodeficiency virus (HIV)-1-infected individuals are affected by diseases at rates above those of their HIV-negative peers despite the increased life expectancy of the highly active antiretroviral therapy era. We followed a cohort of approximately 2000 HIV-1-infected patients for 5 years. The most frequent cause of death in this HIV-1-infected cohort was malignancy, with 39% of all classified deaths due to cancer. Among the cancer deaths, B-cell lymphomas were the most commonly seen malignancy, representing 34% of all cancer deaths. These lymphomas were very aggressive with a median survival of <2 months from time of diagnosis.

Indexed as

B cellHIV-1lymphomamalignancymortality

Identifiers

PMID26566539
PMCPMC4630453
OpenAlexW2175977942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.