Evidence map›Paper›PMID 26566413›Full record

ArticleJournal of clinical medicine research2015

Serum Copeptin, Pentraxin 3, Anti-Mullerian Hormone Levels With Echocardiography and Carotid Artery Intima-Media Thickness in Adolescents With Polycystic Ovary Syndrome.

Mehmet Deveer, Ruya Deveer, Ozcan Basaran, Ummuhani Ozel Turkcu, Eren Akbaba, Nesat Cullu, Nilgun Turhan, Mert Kucuk, Burcu Kasap

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical medicine research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mehmet DeveerDepartment of Radiology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Ruya DeveerDepartment of Obstetrics and Gynecology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Ozcan BasaranDepartment of Cardiology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Ummuhani Ozel TurkcuDepartment of Medical Biochemistry, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Eren AkbabaDepartment of Obstetrics and Gynecology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Nesat CulluDepartment of Radiology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Nilgun TurhanDepartment of Obstetrics and Gynecology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Mert KucukDepartment of Obstetrics and Gynecology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Burcu KasapDepartment of Obstetrics and Gynecology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Muğla University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study was to investigate the presence of possible markers in the prediction of polycystic ovary syndrome (PCOS)-related metabolic alterations and cardiovascular events in adolescent PCOS cases and also to investigate the applicability of anti-Mullerian hormone (AMH) levels for the diagnosis of PCOS.

methodsIn this cross-sectional study, a total of 75 non-obese women (adolescent PCOS group, n = 25; adult PCOS group, n = 25; control group, n = 25) were included. Measurements of copeptin, pentraxin 3 (PTX3), and AMH serum levels were performed.

resultsSerum copeptin, PTX3 and echocardiographic indices were not significantly different in PCOS subjects and they did not have higher common carotid artery intima-media thickness (CIMT) measurement. AMH levels were significantly higher in PCOS patients. There was a positive correlation between AMH and mean ovarian volume (r = 0.58, P < 0.001) and between AMH and total testosterone level (r = 0.63, P < 0.001). In order to predict a threshold value for the diagnosis of PCOS by using AMH, the receiver operating characteristic (ROC) method was used. Area under the curve was 0.820 and cut-off point was 6.66 ng/mL for AMH with a sensitivity of 62% and specificity of 76%.

conclusionsPossible markers for PCOS-related metabolic alterations may not present in the adolescent years. Serum AMH may be useful as a diagnostic test for adolescents.

Indexed as

adolescentAMHCopeptinPCOSPTX3

Identifiers

PMID26566413
PMCPMC4625820
OpenAlexW1831551440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.