Evidence map›Paper›PMID 26566371›Full record

ReviewClinical and experimental gastroenterology2015

Fecal microbiota transplantation: current clinical efficacy and future prospects.

Kathryn A Bowman, Elizabeth K Broussard, Christina M Surawicz

Abstract readReview
In one paragraph

Review in Clinical and experimental gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Metabolic complexity drives divergence in microbial communities.bioRxiv : the preprint server for biology · 2023
    Article
  9. Review
  10. The gut microbiota and endometriosis: From pathogenesis to diagnosis and treatment.Frontiers in cellular and infection microbiology · 2022
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Diagnosis ofIranian journal of microbiology · 2018
    Article
  17. Faecal microbiota transplantation in patients withWorld journal of gastroenterology · 2017
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathryn A BowmanDepartment of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Elizabeth K BroussardDivision of Gastroenterology, University of Washington School of Medicine, Seattle, WA, USA.
Christina M SurawiczDivision of Gastroenterology, University of Washington School of Medicine, Seattle, WA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal microbiota transplantation (FMT) has gained mainstream attention with its remarkable efficacy in treating recurrent Clostridium difficile infection (RCDI) when there are no other effective therapies. Methods of selecting donors and routes of administration vary among studies, but there are now randomized controlled trials showing efficacy of FMT in treating RCDI. Ongoing trials of FMT for other disease such as inflammatory bowel disease are underway; this therapy should not be used for these conditions unless there is strong evidence for efficacy. Long-term safety data are sorely needed, as well as clarification of regulatory concerns.

Indexed as

Clostridium difficile infectionfecal microbiota transplantinflammatory bowel diseasemicrobiomerecurrent Clostridium difficile infection

Identifiers

PMID26566371
PMCPMC4627401

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.