ReviewJournal of clinical orthopaedics and trauma2015
Management of infection following reconstruction in bone tumors.
Review in Journal of clinical orthopaedics and trauma, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Antibacterial Titanium Implants Biofunctionalized by Plasma Electrolytic Oxidation with Silver, Zinc, and Copper: A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Management of infected extremity endoprostheses: a systematic review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2020Pooled it
- Copper coated β-tricalcium phosphate nanoparticles with enhanced antimicrobial and selective anticancer activity: structural, optical, and biological insights.Bioprocess and biosystems engineering · 2026Article
- Microbiological Characteristics and Clinical Outcomes of Periprosthetic Infections Following Oncologic Megaprosthetic Reconstruction: A Retrospective Cohort Study.Pathogens (Basel, Switzerland) · 2026Article
- Strontium and Zinc Co-Doped Mesoporous Bioactive Glass Nanoparticles for Potential Use in Bone Tissue Engineering Applications.Nanomaterials (Basel, Switzerland) · 2024Article
- Risk factors for peri-megaprosthetic joint infections in tumor surgery: A systematic review.SICOT-J · 2024Article
- Evaluation of Absolute Neutrophil Count in the Perioperative Setting of Sarcoma Resection.Advances in orthopedics · 2024Article
- The Intraoperative Use of Defensive Antibacterial Coating (DACMaterials (Basel, Switzerland) · 2023Review
- Staged Management of Infection with Adjustable Spacers After Megaprosthesis Implantation in Primary Sarcoma Patients.Indian journal of orthopaedics · 2023Article
- Iodine-supported implants in prevention and treatment of surgical site infections for compromised hosts: a prospective study.Journal of orthopaedic surgery and research · 2023Article
- Multifunctional Zn and Ag co-doped bioactive glass nanoparticles for bone therapeutic and regeneration.Scientific reports · 2023Article
- Infections of Tumor Prostheses: An Updated Review on Risk Factors, Microbiology, Diagnosis, and Treatment Strategies.Biology · 2023Review
- Biodegradable Bone Implants as a New Hope to Reduce Device-Associated Infections-A Systematic Review.Bioengineering (Basel, Switzerland) · 2022Review
- Endoprosthetic Reconstruction in Ewing's Sarcoma Patients: A Systematic Review of Postoperative Complications and Functional Outcomes.Journal of clinical medicine · 2022Review
- Treatment of Periprosthetic Joint Infection and Fracture-Related Infection With a Temporary Arthrodesis Made by PMMA-Coated Intramedullary Nails - Evaluation of Technique and Quality of Life in Implant-Free Interval.Frontiers in surgery · 2022Article
- Antibacterial hydrogel coating in joint mega-prosthesis: results of a comparative series.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021Article
- Outcomes of Tumor Resection and Reconstruction by Megaprosthesis around Knee: Our Experience.Journal of orthopaedic case reports · 2021Article
- Application of Raman Spectroscopic Imaging to Assess the Structural Changes at Cell-Scaffold Interface.International journal of molecular sciences · 2021Article
- Selected Nanomaterials' Application Enhanced with the Use of Stem Cells in Acceleration of Alveolar Bone Regeneration during Augmentation Process.Nanomaterials (Basel, Switzerland) · 2020Review
- The Potential Innovative Use of Bacteriophages Within the DACFrontiers in medicine · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limb salvage surgery in bone tumors has evolved in recent years and includes all of the surgical procedures designed to accomplish removal of a malignant tumor and reconstruction of the limb with an acceptable oncologic, functional, and cosmetic result. This dramatic change came about as the result of three important developments, i.e. effective chemotherapy, improved precision imaging techniques and advances in reconstructive surgery. Reconstruction with a modular custom-made oncological endoprosthesis (megaprosthesis) has become a common procedure nowadays. These large foreign bodies make infection a common and feared complication. However, the occurrence of complications may be multifactorial, including a poor nutritional and compromised immune status due to chemotherapy and/or radiotherapy, a lengthy operation, extensive dissection and resection of soft tissues, inadequate soft-tissue coverage, a longer exposure of the wound resulting in infection, etc. Management of postoperative infection in these cases remains a challenge. This article analyses the current literature available for these cases and summarizes the cause and different available methods of treatment.
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