ArticlePloS one2015
Validation of Six Short and Ultra-short Screening Instruments for Depression for People Living with HIV in Ontario: Results from the Ontario HIV Treatment Network Cohort Study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Developing an app-based self-management program for people living with HIV: a randomized controlled pilot study during the COVID-19 pandemic.Scientific reports · 2022Trial
- Trial
- Using Latent Profile Analysis to Identify Stigma Typologies Among a Sample of Women Living with HIV and Who Inject Drugs in Ukraine.AIDS and behavior · 2026Article
- Validity and Reliability of the Kessler 6 Scale for Serious Mental Illness Among Populations with High Burden of HIV.AIDS and behavior · 2025Article
- Validity and Reliability of the Filipino Version of the Kessler Psychological Distress Scale.Cureus · 2025Article
- Resilience and ART Adherence Among a Sample of Racially and Ethnically Diverse Sexual Minority Men With HIV.AIDS research and treatment · 2025Article
- Psychometric properties of the ultra-brief self-report Patient Health Questionnaire-4 (PHQ-4) to assess anxiety and depression in Arabic-speaking adults.BMC psychiatry · 2024Article
- Depressive Symptoms, the Impact on ART Continuation, and Factors Associated with Symptom Improvement Among a Cohort of People Living with HIV in British Columbia, Canada.AIDS and behavior · 2024Article
- Undiagnosed Cognitive Impairment and Impact on Instrumental Activities of Daily Living Among People With HIV Infection in Primary Care.Open forum infectious diseases · 2023Article
- Risk Behaviors Associated with Patterns of Sexualized Stimulant and Alcohol Use among Men Who Have Sex with Men: a Latent Class Analysis.Journal of urban health : bulletin of the New York Academy of Medicine · 2022Article
- Examining HIV Stigma, Depression, Stress, and Recent Stimulant Use in a Sample of Sexual Minority Men Living with HIV: An Application of the Stigma and Substance Use Process Model.AIDS and behavior · 2022Article
- Brief Screening Tool for Stepped-Care Management of Mental and Substance Use Disorders.Psychiatric services (Washington, D.C.) · 2021Article
- HIV Injection Risk Behaviors among HIV-Negative People Who Inject Drugs Experiencing Homelessness, 23 U.S. Cities.Journal of social distress and the homeless · 2020Article
- Depressive symptoms and substance use: Changes overtime among a cohort of HIV-positive and HIV-negative MSM.Drug and alcohol dependence · 2020Article
- The Impact of Past and Current Alcohol Consumption Patterns on Progression of Carotid Intima-Media Thickness Among Women and Men Living with HIV Infection.Alcoholism, clinical and experimental research · 2019Article
- Association Between Depressive Symptom Patterns and Clinical Profiles Among Persons Living with HIV.AIDS and behavior · 2018Article
- Article
- Association between alcohol consumption trajectories and clinical profiles among women and men living with HIV.The American journal of drug and alcohol abuse · 2018Article
- Sociodemographic and Health Profile of Heterosexual Men Living With HIV in Ontario, Canada.American journal of men's health · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveMajor depression affects up to half of people living with HIV. However, among HIV-positive patients, depression goes unrecognized 60-70% of the time in non-psychiatric settings. We sought to evaluate three screening instruments and their short forms to facilitate the recognition of current depression in HIV-positive patients attending HIV specialty care clinics in Ontario.
methodsA multi-centre validation study was conducted in Ontario to examine the validity and accuracy of three instruments (the Center for Epidemiologic Depression Scale [CESD20], the Kessler Psychological Distress Scale [K10], and the Patient Health Questionnaire depression scale [PHQ9]) and their short forms (CESD10, K6, and PHQ2) in diagnosing current major depression among 190 HIV-positive patients in Ontario. Results from the three instruments and their short forms were compared to results from the gold standard measured by Mini International Neuropsychiatric Interview (the "M.I.N.I.").
resultsOverall, the three instruments identified depression with excellent accuracy and validity (area under the curve [AUC]>0.9) and good reliability (Kappa statistics: 0.71-0.79; Cronbach's alpha: 0.87-0.93). We did not find that the AUCs differed in instrument pairs (p-value>0.09), or between the instruments and their short forms (p-value>0.3). Except for the PHQ2, the instruments showed good-to-excellent sensitivity (0.86-1.0) and specificity (0.81-0.87), excellent negative predictive value (>0.90), and moderate positive predictive value (0.49-0.58) at their optimal cut-points.
conclusionAmong people in HIV care in Ontario, Canada, the three instruments and their short forms performed equally well and accurately. When further in-depth assessments become available, shorter instruments might find greater clinical acceptance. This could lead to clinical benefits in fast-paced speciality HIV care settings and better management of depression in HIV-positive patients.
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