ArticleAIDS care2016
HIV cure research in South Africa: a preliminary exploration of stakeholder perspectives.
Article in AIDS care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Importance of Social Engagement in the Development of an HIV Cure: A Systematic Review of Stakeholder Perspectives.AIDS and behavior · 2023Pooled it
- Analytical treatment interruption among women with HIV in southern Africa who received VRC01 or placebo in the Antibody Mediated Prevention Study: ATI stakeholder engagement, implementation and early clinical data.Journal of the International AIDS Society · 2025Trial
- Perceptions of young people living with HIV and caregivers in Botswana on analytical treatment interruption studies: a qualitative approach.HIV research & clinical practice · 2026Article
- Understanding of HIV cure research in a rural community with high prevalence: the case of uMkhanyakude district, KwaZulu-Natal, South Africa.AIDS research and therapy · 2025Article
- Beliefs about HIV cure: A qualitative study of people living with HIV in Soweto, South Africa.Southern African journal of HIV medicine · 2025Article
- Antiretroviral pause for HIV remission trials: A mixed methods study of people living with HIV in Soweto, South Africa.PLOS global public health · 2025Article
- 'With this study, we have hope that something is coming': community members' perceptions of HIV cure-related research in Durban, South Africa - a qualitative focus group study.HIV research & clinical practice · 2023Article
- Healthcare Provider Perspectives on HIV Cure Research in Ghana.AIDS research and treatment · 2023Article
- Community HIV clinicians' perceptions about HIV cure-related research in the Northwestern United States.HIV research & clinical practice · 2022Article
- Assessing potential cures: are there distinctive elements of value beyond health gain?Journal of comparative effectiveness research · 2021Article
- Unwillingness of patients in Ghana to interrupt antiretroviral therapy for HIV cure research.Journal of virus eradication · 2021Article
- The case for an HIV cure and how to get there.The lancet. HIV · 2021Review
- Re-examining the HIV 'functional cure' oxymoron: Time for precise terminology?Journal of virus eradication · 2020Article
- Article
- Differences in HIV cure clinical trial preferences of French people living with HIV and physicians in the ANRS-APSEC study: a discrete choice experiment.Journal of the International AIDS Society · 2020Article
- Forming and implementing community advisory boards in low- and middle-income countries: a scoping review.BMC medical ethics · 2019Article
- Revisiting the 'sterilising cure' terminology: a call for more patient-centred perspectives on HIV cure-related research.Journal of virus eradication · 2019Article
- The psychology of "cure" - unique challenges to consent processes in HIV cure research in South Africa.BMC medical ethics · 2019Article
- Ethical challenges in developing an educational video to empower potential participants during consent processes in HIV cure research in South Africa.Journal of virus eradication · 2018Article
- Arresting Leprosy: Therapeutic Outcomes Besides Cure.American journal of public health · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Innovative strategies for HIV cure are in development and research studies are being designed and planned globally. South Africa is no exception. However, little is known about stakeholders' knowledge, understanding and expectations of future cure research. This study aimed to obtain in-depth qualitative insights into stakeholder perspectives at this formative stage of HIV cure research. Fifteen stakeholders were interviewed in an HIV research clinic in the Western Cape, South Africa with their consent. Interviews were transcribed verbatim and analysed using thematic content analysis. Broad themes that emerged included the meaning of cure, awareness of HIV cure research, risks and benefits of such research. General awareness and understanding of HIV cure research was lower than expected. Some participants expressed a fatalistic attitude to HIV and described it as an "end-time illness" with no prospect of cure. In general, HIV cure research was regarded as risky - biologically psychologically and socially. If study designs were to include treatment interruption, participants would comply only if success was guaranteed. Given these perceptions of HIV cure research, significant challenges to consent processes and participant recruitment can be anticipated. Authentic community engagement and intensive educational interventions will be necessary prior to future cure research in South Africa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.