ArticleEpidemiology and infection2016
Estimating the number of cases of acute gastrointestinal illness (AGI) associated with Canadian municipal drinking water systems.
Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Burden of disease from contaminated drinking water in countries with high access to safely managed water: A systematic review.Water research · 2023Pooled it
- Quantitative microbial risk assessment of acute gastrointestinal illness attributable to freshwater recreation in Ontario.Canadian journal of public health = Revue canadienne de sante publique · 2025Article
- Relationship between extreme precipitation and acute gastrointestinal illness in Toronto, Ontario, 2012-2022.Epidemiology and infection · 2024Article
- Statewide Quantitative Microbial Risk Assessment for Waterborne Viruses, Bacteria, and Protozoa in Public Water Supply Wells in Minnesota.Environmental science & technology · 2022Article
- Quantitative Microbial Risk Assessment for Contaminated Private Wells in the Fractured Dolomite Aquifer of Kewaunee County, Wisconsin.Environmental health perspectives · 2021Article
- Estimate of Burden and Direct Healthcare Cost of Infectious Waterborne Disease in the United States.Emerging infectious diseases · 2021Article
- Estimates of healthcare utilisation and deaths from waterborne pathogen exposure in Ontario, Canada.Epidemiology and infection · 2020Article
- Potential Public Health Impacts of Deteriorating Distribution System Infrastructure.Journal - American Water Works Association · 2019Article
- Wastewater treatment and public health in Nunavut: a microbial risk assessment framework for the Canadian Arctic.Environmental science and pollution research international · 2018Review
- Time series study of weather, water quality, and acute gastroenteritis at Water Safety Plan implementation sites in France and Spain.International journal of hygiene and environmental health · 2018Article
- Estimates of the burden of illness for eight enteric pathogens associated with animal contact in Canada.Epidemiology and infection · 2017Article
- Drinking Water Management and Governance in Canada: An Innovative Plan-Do-Check-Act (PDCA) Framework for a Safe Drinking Water Supply.Environmental management · 2017Article
- Estimating the burden of acute gastrointestinal illness due to Giardia, Cryptosporidium, Campylobacter, E. coli O157 and norovirus associated with private wells and small water systems in Canada.Epidemiology and infection · 2016Article
- Quantitative microbial risk assessment with microbial source tracking for enteric pathogens in southwest Wisconsin private wells.Journal of environmental qualityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The estimated burden of endemic acute gastrointestinal illness (AGI) annually in Canada is 20·5 million cases. Approximately 4 million of these cases are domestically acquired and foodborne, yet the proportion of waterborne cases is unknown. A number of randomized controlled trials have been completed to estimate the influence of tap water from municipal drinking water plants on the burden of AGI. In Canada, 83% of the population (28 521 761 people) consumes tap water from municipal drinking water plants serving >1000 people. The drinking water-related AGI burden associated with the consumption of water from these systems in Canada is unknown. The objective of this research was to estimate the number of AGI cases attributable to consumption of drinking water from large municipal water supplies in Canada, using data from four household drinking water intervention trials. Canadian municipal water treatment systems were ranked into four categories based on source water type and quality, population size served, and treatment capability and barriers. The water treatment plants studied in the four household drinking water intervention trials were also ranked according to the aforementioned criteria, and the Canadian treatment plants were then scored against these criteria to develop four AGI risk groups. The proportion of illnesses attributed to distribution system events vs. source water quality/treatment failures was also estimated, to inform the focus of future intervention efforts. It is estimated that 334 966 cases (90% probability interval 183 006-501 026) of AGI per year are associated with the consumption of tap water from municipal systems that serve >1000 people in Canada. This study provides a framework for estimating the burden of waterborne illness at a national level and identifying existing knowledge gaps for future research and surveillance efforts, in Canada and abroad.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.