Evidence map›Paper›PMID 26564433›Full record

GuidelineAJNR. American journal of neuroradiology2016

Revised Recommendations of the Consortium of MS Centers Task Force for a Standardized MRI Protocol and Clinical Guidelines for the Diagnosis and Follow-Up of Multiple Sclerosis.

A Traboulsee, J H Simon, L Stone, E Fisher, D E Jones, A Malhotra, S D Newsome, J Oh, D S Reich, N Richert and 6 more

Abstract readPractice Guideline
In one paragraph

Guideline in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  5. FLAIRNeuroImage. Clinical · 2019
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74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

A TraboulseeFrom the Department of Medicine (Neurology) (A.T.), University of British Columbia, Vancouver, Canada t.traboulsee@ubc.ca.ORCID http://orcid.org/0000-0002-0351-9639
J H SimonPortland VA Research Foundation and Oregon Health and Sciences University (J.H.S.), Portland, Oregon.
L StoneMellen Center for MS Treatment and Research (L.S.), Cleveland Clinic, Cleveland, Ohio.
E FisherDepartment of Biomedical Engineering, Cleveland Clinic (E.F.). Cleveland, Ohio.
D E JonesDepartment of Neurology, University of Virginia (D.E.J.), Charlottesville, Virginia.
A MalhotraDepartment of Radiology and Biomedical Imaging, Yale University (A.M.), New Haven, Connecticut.
S D NewsomeDepartment of Neurology (S.D.N.), Johns Hopkins School of Medicine, Baltimore, Maryland.
J OhSt. Michael's Hospital (J.O.), University of Toronto, Toronto, Ontario, Canada.
D S ReichTranslational Neuroradiology Unit (D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.ORCID http://orcid.org/0000-0002-2628-4334
N RichertBiogen Idec (N.R.), Cambridge, Massachusetts.
K RammohanUniversity of Miami Multiple Sclerosis Center (K.R.), Miami, Florida.
O KhanDepartment of Neurology (O.K.), Wayne State University School of Medicine, Detroit, Michigan.
E-W RadueDepartment of Radiology (E.-W.R.), University Hospital, Basel, Switzerland.
C FordUniversity of New Mexico Health Science Center (C.F.), Albuquerque, New Mexico.
J HalperConsortium of Multiple Sclerosis Centers (J.H.), Hackensack, New Jersey.
D LiDepartments of Radiology (D.L.), University of British Columbia, Vancouver, British Columbia Canada.ORCID http://orcid.org/0000-0002-1121-5571

Funding

Multimodal MRI in Multiple SclerosisZIANS003119 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI REICH, DANIEL · 2010 to 2025
$53.4M
Intramural NIH HHS Z99 NS999999Intramural NIH HHS ZIA NS003119
6 · The paper itself

Abstract

An international group of neurologists and radiologists developed revised guidelines for standardized brain and spinal cord MR imaging for the diagnosis and follow-up of MS. A brain MR imaging with gadolinium is recommended for the diagnosis of MS. A spinal cord MR imaging is recommended if the brain MR imaging is nondiagnostic or if the presenting symptoms are at the level of the spinal cord. A follow-up brain MR imaging with gadolinium is recommended to demonstrate dissemination in time and ongoing clinically silent disease activity while on treatment, to evaluate unexpected clinical worsening, to re-assess the original diagnosis, and as a new baseline before starting or modifying therapy. A routine brain MR imaging should be considered every 6 months to 2 years for all patients with relapsing MS. The brain MR imaging protocol includes 3D T1-weighted, 3D T2-FLAIR, 3D T2-weighted, post-single-dose gadolinium-enhanced T1-weighted sequences, and a DWI sequence. The progressive multifocal leukoencephalopathy surveillance protocol includes FLAIR and DWI sequences only. The spinal cord MR imaging protocol includes sagittal T1-weighted and proton attenuation, STIR or phase-sensitive inversion recovery, axial T2- or T2*-weighted imaging through suspicious lesions, and, in some cases, postcontrast gadolinium-enhanced T1-weighted imaging. The clinical question being addressed should be provided in the requisition for the MR imaging. The radiology report should be descriptive, with results referenced to previous studies. MR imaging studies should be permanently retained and available. The current revision incorporates new clinical information and imaging techniques that have become more available.

Indexed as

BrainFemaleFollow-Up StudiesGadolinium DTPAHumansMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisNeuroimagingSpinal CordGadolinium DTPA

Identifiers

PMID26564433
PMCPMC5094650

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.