SynthesisJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2016
Sleep Disturbances in Traumatic Brain Injury: A Meta-Analysis.
Synthesis in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- Sleep in patients with traumatic brain injury: a systematic review and meta-analysis of actigraphy studies.Sleep · 2025Pooled it
- Prevalence of sleep-disordered breathing in people with tetraplegia-a systematic review and meta-analysis.Spinal cord · 2021Pooled it
- The risk factors for insomnia and sleep-disordered breathing in military communities: A meta-analysis.PloS one · 2021Pooled it
- Poorer sleep quality predicts melatonin response in patients with traumatic brain injury: findings from a randomized controlled trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Trial
- Brain clearance physiology in traumatic brain injury: From disruption to therapeutic potential.The Journal of physiology · 2026Article
- Multidimensional sleep health and serious cognitive difficulty among US adolescents.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Primary Blast-Induced Traumatic Brain Injury as a Risk Factor for (Cerebro)vascular Disorder: Clinical Manifestations, Blast Physics, Biomechanics, Pathobiology, and Critical Gaps.International journal of molecular sciences · 2026Review
- Sleep fragmentation intensifies sleep architecture disruption and fatigue after traumatic brain injury.Experimental neurology · 2026Article
- Pilot Neuroimaging Evidence of Altered Resting Functional Connectivity of the Brain Associated with Poor Sleep After Acquired Brain Injury.Journal of clinical medicine · 2026Article
- Impacts of traumatic brain injury severity and sex on sleep architecture, duration, and fragmentation.Neurobiology of sleep and circadian rhythms · 2025Article
- Understanding discrepancies between self-reported and objective sleep in adolescents and young adults with subacute concussion.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Increased Risk for Clinically Significant Sleep Disturbances in Mild Traumatic Brain Injury: An Approach to Leveraging the Federal Interagency Traumatic Brain Injury Research Database.Brain sciences · 2024Article
- Article
- Factors influencing shared decision-making for insomnia and obstructive sleep apnea treatment among Veterans with mild traumatic brain injury.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Sleep quality and psychological health in patients with pelvic and acetabulum fractures: a cross-sectional study.BMC geriatrics · 2024Article
- Health-related quality of life among inpatients suffering from Traumatic brain injury in an urban setting in Vietnam.PloS one · 2024Article
- Feasibility of delivering a randomized controlled trial of weighted blanket intervention to help agitation and disturbed sleep after brain injury.Frontiers in sleep · 2024Article
- Traumatic brain injury and sleep in military and veteran populations: A literature review.NeuroRehabilitation · 2024Review
- Sex Differences in Sleep Architecture After Traumatic Brain Injury: Potential Implications on Short-Term Episodic Memory and Recovery.Neurotrauma reports · 2024Article
- Epidemiology of Traumatic Brain Injury in Iran: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2023Review
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesSleep disturbances are frequently reported following traumatic brain injury (TBI); however, the exact disturbances remain unclear. This meta-analysis aimed to characterize sleep disturbance in community dwelling patients with TBI as compared to controls.
methodsTwo investigators independently conducted a systematic search of multiple electronic databases from inception to May 27, 2015. Studies were selected if they compared sleep in community dwelling individuals with TBI relative to a control population without head injury. Data were pooled in meta-analysis with outcomes expressed as the standard mean difference (SMD) and 95% confidence interval (CI). The primary outcomes were derived from polysomnography and secondary outcomes were derived from subjective sleep measures.
resultsSixteen studies were included, combining 637 TBI patients and 567 controls, all of whom were community dwelling. Pooled polysomnography data revealed that TBI patients had poorer sleep efficiency (SMD = -0.47, CI: -0.89, -0.06), shorter total sleep duration (SMD = -0.37, CI: -0.59, -0.16), and greater wake after sleep onset time (SMD = 0.60, CI: 0.33, 0.87). Although sleep architecture was similar between the groups, a trend suggested that TBI patients may spend less time in REM sleep (SMD = -0.22, CI: -0.45, 0.01). Consistent with polysomnographic derangement, TBI patients reported greater subjective sleepiness and poorer perceived sleep quality.
conclusionsThe evidence suggests that TBI is associated with widespread objective and subjective sleep deficits. The present results highlight the need for physicians to monitor and address sleep deficits following TBI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.