ArticlePlant physiology2016
The RING Finger Ubiquitin E3 Ligase OsHTAS Enhances Heat Tolerance by Promoting H2O2-Induced Stomatal Closure in Rice.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
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Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 240 citations in OpenAlex.
- Pooled it
- Temperature regulation in plants: From molecular mechanisms to climate-resilient crop improvement.Journal of integrative plant biology · 2026Review
- Integrating molecular networks and physiological adaptation for heat-resilient crops.Journal of integrative plant biology · 2026Review
- The miR396f-GRF7 Module Confers Thermotolerance in Rice.Rice (New York, N.Y.) · 2026Article
- Article
- Identification of candidate genes for heat tolerance in rice by genome-wide association study and transcriptome sequencing.BMC plant biology · 2026Article
- Kelch-type F-box protein TaFBK34 improves wheat seedling tolerance to heat stress.BMC biology · 2025Article
- Genetic and Molecular Basis for Heat Tolerance in Rice: Strategies for Resilience Under Climate Change.Plants (Basel, Switzerland) · 2025Review
- Rice Heat Stress Response: Physiological Changes and Molecular Regulatory Network Research Progress.Plants (Basel, Switzerland) · 2025Review
- Heat Priming and Heat Stress Enhance Transgenerational Heat Tolerance in the Early Growth Stages ofPlants (Basel, Switzerland) · 2025Article
- Combined Analysis of Transcriptome and Metabolome Reveals the Heat Stress Resistance of Dongxiang Wild Rice at Seedling Stage.Plants (Basel, Switzerland) · 2025Article
- Review
- Evaluating Physiological and Hormonal Responses of Two Distinct Rice Genotypes Under High Temperatures.Plants (Basel, Switzerland) · 2025Article
- A molecular module improves rice grain quality and yield at high temperatures.National science review · 2025Article
- The NAT1-bHLH110-CER1/CER1L module regulates heat stress tolerance in rice.Nature genetics · 2025Article
- Decrypting molecular mechanism of heat stress tolerance in rice to tackle climate change challenges through recent approaches.Frontiers in plant science · 2025Review
- ZmHSFA2B self-regulatory loop is critical for heat tolerance in maize.Plant biotechnology journal · 2025Article
- How Rice Responds to Temperature Changes and Defeats Heat Stress.Rice (New York, N.Y.) · 2024Review
- Deciphering the mechanism of E3 ubiquitin ligases in plant responses to abiotic and biotic stresses and perspectives on PROTACs for crop resistance.Plant biotechnology journal · 2024Review
- The MdHSC70-MdWRKY75 module mediates basal apple thermotolerance by regulating the expression of heat shock factor genes.The Plant cell · 2024Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat stress often results in the generation of reactive oxygen species, such as hydrogen peroxide, which plays a vital role as a secondary messenger in the process of abscisic acid (ABA)-mediated stomatal closure. Here, we characterized the rice (Oryza sativa) HEAT TOLERANCE AT SEEDLING STAGE (OsHTAS) gene, which plays a positive role in heat tolerance at the seedling stage. OsHTAS encodes a ubiquitin ligase localized to the nucleus and cytoplasm. OsHTAS expression was detected in all tissues surveyed and peaked in leaf blade, in which the expression was concentrated in mesophyll cells. OsHTAS was responsive to multiple stresses and was strongly induced by exogenous ABA. In yeast two-hybrid assays, OsHTAS interacted with components of the ubiquitin/26S proteasome system and an isoform of rice ascorbate peroxidase. OsHTAS modulated hydrogen peroxide accumulation in shoots, altered the stomatal aperture status of rice leaves, and promoted ABA biosynthesis. The results suggested that the RING finger ubiquitin E3 ligase OsHTAS functions in leaf blade to enhance heat tolerance through modulation of hydrogen peroxide-induced stomatal closure and is involved in both ABA-dependent and DROUGHT AND SALT TOLERANCE-mediated pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.