SynthesisPreventing chronic disease2015
Systematic Review of Programs Treating High-Need and High-Cost People With Multiple Chronic Diseases or Disabilities in the United States, 2008-2014.
Synthesis in Preventing chronic disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Pooled it
- Prediction Models for Future High-Need High-Cost Healthcare Use: a Systematic Review.Journal of general internal medicine · 2022Pooled it
- Adjusted Indirect and Mixed Comparisons of Interventions for the Patient-Reported Outcomes Measures (PROMs) of Disabled Adults: A Systematic Review and Network Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Underlying mechanisms of complex interventions addressing the care of older adults with multimorbidity: a realist review.BMJ open · 2019Pooled it
- Pooled it
- Patient Activation, Depressive Symptoms, and Self-Rated Health: Care Management Intervention Effects among High-Need, Medically Complex Adults.International journal of environmental research and public health · 2021Trial
- Primary Care Providers' Acceptance of Pharmacists' Recommendations to Support Optimal Medication Management for Patients with Diabetic Kidney Disease.Journal of general internal medicine · 2020Trial
- Lessons learned from a trial on integrated and proactive care for patients with complex needs (Hotspotters project): a process evaluation.medRxiv : the preprint server for health sciences · 2026Article
- Sex differences in the burden of multiple long-term conditions among Japanese individuals with heart failure.Open heart · 2025Article
- Compliance with clinical guidelines: the role of incentives and competition between practitioners.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Article
- Evaluation of Activities of Daily Living: Current Insights and Future Horizons.Annals of geriatric medicine and research · 2025Review
- Caring for Patients with Functional Impairment in Middle Age: Perspectives from Primary Care Providers and Geriatricians.Journal of general internal medicine · 2024Article
- Experiences of participants in the co-design of a community-based health service for people with high healthcare service use.BMC health services research · 2024Article
- Therapeutic potential of natural products in inflammation: underlying molecular mechanisms, clinical outcomes, technological advances, and future perspectives.Inflammopharmacology · 2023Review
- Caring for high-need patients.BMC health services research · 2023Article
- Article
- Machine Learning Model for Predicting Mortality Risk in Patients With Complex Chronic Conditions: Retrospective Analysis.Online journal of public health informatics · 2023Article
- Unpacking complex interventions that manage care for high-need, high-cost patients: a realist review.BMJ open · 2022Review
- Care Coordination Models and Tools-Systematic Review and Key Informant Interviews.Journal of general internal medicine · 2022Article
Corrections and comments
- Commented on by
- Erratum issuedErratum, Vol. 12, November 12 Release.2016 · Chang, Eva [corrected to DuGoff, Eva]
Authors and funding
11 authors.
Funding
Abstract
introductionFinding ways to provide better and less expensive health care for people with multiple chronic conditions or disability is a pressing concern. The purpose of this systematic review was to evaluate different approaches for caring for this high-need and high-cost population.
methodsWe searched Medline for articles published from May 31, 2008, through June 10, 2014, for relevant studies. Articles were considered eligible for this review if they met the following criteria: included people with multiple chronic conditions (behavioral or mental health) or disabilities (2 or more); addressed 1 or more of clinical outcomes, health care use and spending, or patient satisfaction; and compared results from an intervention group with a comparison group or baseline measurements. We extracted information on program characteristics, participant characteristics, and significant (positive and negative) clinical findings, patient satisfaction, and health care use outcomes. For each outcome, the number of significant and positive results was tabulated.
resultsTwenty-seven studies were included across 5 models of care. Of the 3 studies reporting patient satisfaction outcomes, 2 reported significant improvements; both were randomized controlled trials (RCTs). Of the 14 studies reporting clinical outcomes, 12 reported improvements (8 were RCTs). Of the 13 studies reporting health care use and spending outcomes, 12 reported significant improvements (2 were RCTs). Two models of care - care and case management and disease management - reported improvements in all 3 outcomes. For care and case management models, most improvements were related to health care use. For the disease management models, most improvements were related to clinical outcomes.
conclusionsCare and case management as well as disease management may be promising models of care for people with multiple chronic conditions or disabilities. More research and consistent methods are needed to understand the most appropriate care for these high-need and high-cost patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.