Evidence map›Paper›PMID 26563951›Full record

ArticleJournal of cancer survivorship : research and practice2016

Lost workdays in uterine cervical cancer survivors compared to the general population: impact of treatment and relapse.

Åsa H Everhov, Sara Ekberg, Angelica Lindén Hirschberg, Karin Bergmark, Angelique Flöter Rådestad, Ingrid Glimelius, Karin E Smedby

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Article in Journal of cancer survivorship : research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Åsa H EverhovDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden. asa.hallqvist-everhov@ki.se.
Sara EkbergUnit of Clinical Epidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Angelica Lindén HirschbergDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Karin BergmarkDepartment of Oncology, Sahlgrenska Academy, Gothenburg, Sweden.
Angelique Flöter RådestadDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Ingrid GlimeliusUnit of Clinical Epidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Karin E SmedbyUnit of Clinical Epidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the present study was to examine the risk of lost workdays due to sick leave and disability pension by treatment modality and relapse in a population-based cohort of cervical cancer survivors versus matched comparators.

methodsWe identified 1971 cervical cancer patients aged ≤60 years (median 42) at diagnosis in Sweden 2003-2009 and 9254 population comparators. Information on sociodemographic and clinical characteristics, sick leave, and disability pension was retrieved from nationwide prospective registers. Differences in the annual mean number of lost workdays were calculated by linear regression, and hazard ratios (HRs) of disability pension were calculated by Cox regression analysis, with follow-up through September 2013.

resultsCervical cancer patients had more lost workdays annually than comparators up to 8 years following diagnosis. Relapse-free patients had more lost workdays than comparators up to 4 years. Risk of disability pension during follow-up was increased among the relapse-free patients treated with hysterectomy (HR 1.8 [95 % confidence interval (CI) 1.1-2.8]), hysterectomy plus chemotherapy and/or radiotherapy (HR 2.5 [95 % CI 1.2-5.4]), or chemotherapy and/or radiotherapy alone (HR 3.0 [95 % CI 1.3-6.8]), compared with the population. Women treated with fertility-sparing surgery did not have more lost workdays than the population beyond the first year and were not at increased risk of disability pension.

conclusionWe observed a long-standing increased risk of lost workdays among cervical cancer patients, overall, as well as among relapse-free patients. IMPLICATIONS FOR CANCER SURVIVORS: Extensive but not limited treatment was associated with increased risk of lost workdays, possibly reflecting an association between treatment side effects and work ability.

Indexed as

AdultChronic DiseaseCohort StudiesFemaleHumansMaleMiddle AgedPensionsPersons with DisabilitiesProspective StudiesRecurrenceRegistriesSick LeaveSurvivorsSwedenUterine Cervical NeoplasmsChemotherapyDisability pensionHysterectomyRadiotherapySick leaveUterine cervical cancer

Identifiers

PMID26563951

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.