ArticleBMC neurology2015
Quantifying cognition at the bedside: a novel approach combining cognitive symptoms and signs in HIV.
Article in BMC neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The effectiveness of eye tracking in the diagnosis of cognitive disorders: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Effectiveness of a personalized health profile on specificity of self-management goals among people living with HIV in Canada: findings from a blinded pragmatic randomized controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Trial
- Cognition and saccadic eye movement performance are impaired in chronic rhinosinusitis.International forum of allergy & rhinology · 2024Article
- Translocation of bacterial LPS is associated with self-reported cognitive abilities in men living with HIV receiving antiretroviral therapy.AIDS research and therapy · 2023Article
- Development of a self-report measure of cognitive change: assessment of interpretability in two samples, people with HIV and people without HIV.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Efficacy potential of Goal Management Training to improve cognitive function in older people living with HIV.Contemporary clinical trials communications · 2022Article
- Relationship between reward-related evoked potentials and real-world motivation in older people living with human immunodeficiency virus.Frontiers in aging neuroscience · 2022Article
- Action for better brain health among people living with HIV: protocol for a randomized controlled trial.BMC infectious diseases · 2021Article
- Development and validation of a voice-of-the-patient measure of cognitive concerns experienced by people living with HIV.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Relationships between cognition, function, and quality of life among HIV+ Canadian men.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Properties of a brief assessment tool for longitudinal measurement of cognition in people living with HIV.PloS one · 2019Article
- Monitoring HIV-Associated Neurocognitive Disorder Using Screenings: a Critical Review Including Guidelines for Clinical and Research Use.Current HIV/AIDS reports · 2017Review
- Understanding and optimizing brain health in HIV now: protocol for a longitudinal cohort study with multiple randomized controlled trials.BMC neurology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundUp to half of all people with HIV infection have some degree of cognitive impairment. This impairment is typically mild, but nonetheless often disabling. Although early detection of cognitive impairment offers the greatest hope of effective intervention, there are important barriers to this goal in most clinical settings. These include uncertainty about how self-reported cognitive symptoms relate to objective impairments, and the paucity of bedside measurement tools suitable for mild deficits. Clinicians need guidance in interpreting cognitive symptoms in this population, and a brief cognitive measurement tool targeted to mild impairment. We addressed these two problems together here. The objective of this study was to determine the extent to which performance on cognitive tests and self-reported cognitive symptoms form a unidimensional construct.
methodsTwo hundred three HIV+ individuals completed the Montreal Cognitive Assessment, computerized cognitive tasks and a questionnaire eliciting cognitive symptoms. Rasch measurement theory was applied to determine whether patient-reported and performance items could be combined to measure cognition as a unidimensional latent construct.
resultsPerformance-based items and cognitive symptoms are arranged hierarchically along the same continuum of cognitive ability, forming a measure with thresholds covering a broad spectrum of ability that has good internal reliability. The cognitive symptoms that fit the measurement model relate to important aspects of everyday life, providing evidence that the identified construct is meaningful.
conclusionsThis finding lays the foundation for a rapid measure of cognitive ability in people with HIV infection that is feasible for routine clinical use, and shows that some cognitive symptoms are systematically related to performance in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.