Evidence map›Paper›PMID 26563256›Full record

GuidelineCancer chemotherapy and pharmacology2016

Clinical practice guidelines for the diagnosis and treatment of patients with soft tissue sarcoma by the Spanish group for research in sarcomas (GEIS).

Xavier Garcia del Muro, Enrique de Alava, Vicenç Artigas, Silvia Bague, Alejandro Braña, Ricardo Cubedo, Josefina Cruz, Nuria Mulet-Margalef, Jose A Narvaez, Oscar Martinez Tirado and 5 more

Open access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in Cancer chemotherapy and pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. GEIS-SEHOP clinical practice guidelines for the treatment of rhabdomyosarcoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  10. Article
  11. Outcomes and computed tomography radiomic features extraction in soft tissue sarcomas treated with neoadjuvant radiation therapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2021
    Article
  12. Article
  13. Article
  14. In Reply.The oncologist · 2019
    Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Xavier Garcia del MuroInstitut Català d'Oncologia L'Hospitalet, Barcelona, Spain. garciadelmuro@iconcologia.net.
Enrique de AlavaHospital Universitario Virgen del Rocío, Sevilla, Spain.
Vicenç ArtigasHospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Silvia BagueHospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Alejandro BrañaHospital Central de Asturias, Oviedo, Spain.
Ricardo CubedoHospital Puerta de Hierro Majadahonda, Madrid, Spain.
Josefina CruzHospital Universitario de Canarias, Santa Cruz De Tenerife, Spain.
Nuria Mulet-MargalefInstitut Català d'Oncologia L'Hospitalet, Barcelona, Spain.
Jose A NarvaezHospital Universitario de Bellvitge, Barcelona, Spain.
Oscar Martinez TiradoInstituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona, Spain.
Claudia ValverdeHospital Universitario Vall d'Hebron, Barcelona, Spain.
Ramona VergesHospital Universitario Vall d'Hebron, Barcelona, Spain.
Joan ViñalsHospital Universitario de Bellvitge, Barcelona, Spain.
Javier Martin-BrotoHospital Universitario Virgen del Rocío, Sevilla, Spain.
Spanish Group for Research on Sarcoma
Bellvitge University Hospital · ESHospital de Sant Pau · ESHospital Universitario Virgen del Rocío · ESInstitut Català d'Oncologia · ESVall d'Hebron Hospital Universitari · ESHospital Universitario Central de Asturias · ESHospital Universitario de Canarias · ESHospital Universitario Puerta de Hierro Majadahonda · ESInstitut d'Investigació Biomédica de Bellvitge · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumours, which require a complex and specialized multidisciplinary management. The diagnostic approach should include imaging studies and core needle biopsy performed prior to undertaking surgery. Wide excision is the mainstay of treatment for localized sarcoma, and associated preoperative or postoperative radiotherapy should be administered in high-risk patients. Adjuvant chemotherapy was associated with a modest improvement in survival in a meta-analysis and constitutes a standard option in selected patients with high-risk STS. In metastatic patients, surgery must be evaluated in selected cases. In the rest of patients, chemotherapy and, in some subtypes, targeted therapy often used in a sequential strategy constitutes the treatment of election. Despite important advances in the understanding of the pathophysiology of the disease, the advances achieved in therapeutic results may be deemed still insufficient. Moreover, due to the rarity and complexity of the disease, the results in clinical practice are not always optimal. For this reason, the Spanish Group for Research on Sarcoma (GEIS) has developed a multidisciplinary clinical practice guidelines document, with the aim of facilitating the diagnosis and treatment of these patients in Spain. In the document, each practical recommendation is accompanied by level of evidence and grade of recommendation on the basis of the available data.

Indexed as

Antineoplastic AgentsChemotherapy, AdjuvantHumansSarcomaSoft Tissue NeoplasmsSpainAntineoplastic AgentsClinical practice guidelinesMultidisciplinary managementSoft tissue sarcomaTreatment

Identifiers

PMID26563256
PMCPMC4706580
OpenAlexW2167316237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.