Evidence map›Paper›PMID 26563199›Full record

ArticleMedical & biological engineering & computing2016

Fluid flow and particle transport in mechanically ventilated airways. Part I. Fluid flow structures.

Timothy Van Rhein, Mohammed Alzahrany, Arindam Banerjee, Gary Salzman

Abstract read
PubMed Publisher
In one paragraph

Article in Medical & biological engineering & computing, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Insights from 3D modeling and fluid dynamics in COVID-19 pneumonia.Medical & biological engineering & computing · 2024
    Article
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  5. Article
  6. [Progress in numerical simulation and experimental study on inhalable particles deposition in human respiratory system].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Timothy Van RheinDepartment of Mechanical and Aerospace Engineering, Missouri University of Science and Technology, Rolla, MO, 65409, USA.
Mohammed AlzahranyPackard Laboratory, Department of Mechanical Engineering and Mechanics, Lehigh University, Bethlehem, PA, 18015, USA.
Arindam BanerjeePackard Laboratory, Department of Mechanical Engineering and Mechanics, Lehigh University, Bethlehem, PA, 18015, USA. arb612@lehigh.edu.
Gary SalzmanRespiratory and Critical Care Medicine, University of Missouri- Kansas City School of Medicine, Kansas City, MO, 64108, USA.
Lehigh University · USMissouri University of Science and Technology · USUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A large eddy simulation-based computational study of fluid flow and particle transport in upper tracheobronchial airways is carried out to investigate the effect of ventilation parameters on pulmonary fluid flow. Respiratory waveforms commonly used by commercial mechanical ventilators are used to study the effect of ventilation parameters and ventilation circuit on pulmonary fluid dynamics. A companion paper (Alzahrany et al. in Med Biol Eng Comput, 2014) reports our findings on the effect of the ventilation parameters and circuit on particle transport and aerosolized drug delivery. The endotracheal tube (ETT) was found to be an important geometric feature and resulted in a fluid jet that caused an increase in turbulence and created a recirculation zone with high wall shear stress in the main bronchi. Stronger turbulence was found in lower airways than would be found under normal breathing conditions due to the presence of the jet caused by the ETT. The pressure-controlled sinusoidal waveform induced the lowest wall shear stress on the airways wall.

Indexed as

HydrodynamicsRespiration, ArtificialBronchiComputer SimulationHumansIntubation, IntratrachealMaleMiddle AgedPressureRespirationRespiratory SystemStress, MechanicalTomography, X-Ray ComputedCT scanLarge eddy simulationMechanical ventilationPulmonary flowWaveform

Identifiers

PMID26563199
OpenAlexW2118595395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.