Evidence map›Paper›PMID 26562813›Full record

ArticleAIDS (London, England)2015

Development and pilot testing of an intervention to promote care engagement and adherence among HIV-positive Kenyan MSM.

Susan M Graham, Murugi Micheni, Bernadette Kombo, Elisabeth M Van Der Elst, Peter M Mugo, Esther Kivaya, Frances Aunon, Bryan Kutner, Eduard J Sanders, Jane M Simoni

Registry-linked trialOpen access · hybridAbstract readEvaluation Study
In one paragraph

Article in AIDS (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02301533 (Provider and Peer Support Intervention to Improve ART Adherence Among Kenyan Men Who Have Sex With Men), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02301533 nacompletednot on this map

Provider and Peer Support Intervention to Improve ART Adherence Among Kenyan Men Who Have Sex With Men

TypeinterventionalSponsorUniversity of WashingtonRan2015 to 2016Enrolled60ConditionsMedication AdherenceArmsShikamana Intervention, Standard Care
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 4 countries.

Susan M GrahamaDepartment of Medicine bDepartment of Global Health cDepartment of Epidemiology, University of Washington, Seattle, Washington, USA dCentre for Geographic Medicine Research - Coast, Kenya Medical Research Institute, Kilifi, Kenya eDepartment of Psychology, University of Washington, Seattle, Washington, USA fNuffield Department of Medicine, University of Oxford, Headington, UK gDepartment of Global Health, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
Murugi Micheni
Bernadette Kombo
Elisabeth M Van Der Elst
Peter M Mugo
Esther Kivaya
Frances Aunon
Bryan Kutner
Eduard J Sanders
Jane M Simoni
Kenya Medical Research Institute · KEUniversity of Washington · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Florian Hladik · 1988 to 2026
$104.9M
VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
Provider and Peer Support Intervention to Improve ART Adherence among Kenyan MenR34MH099946 · NIMH · UNIVERSITY OF WASHINGTON · PI GRAHAM, SUSAN MARIE · 2013 to 2015
$627k
Mentoring Diverse Scientists in Global HIV Research on Mental Health & AdherenceK24MH093243 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2011 to 2014
$590k
NIAID NIH HHS P30 AI027757NIAID NIH HHS P30AI027757NIAID NIH HHS T32 AI007140NIMH NIH HHS K24 MH093243NIMH NIH HHS R34 MH099946NIMH NIH HHS R34MH099946Wellcome Trust 077092Wellcome Trust 092654
6 · The paper itself

Abstract

objectivesIn many African settings, MSM are a stigmatized group whose access to and engagement in HIV care may be challenging. Our aim was to design a targeted, culturally appropriate intervention to promote care engagement and antiretroviral therapy (ART) adherence for MSM in coastal Kenya, and describe intervention safety, feasibility, and acceptability based upon a small pilot study.

designBased on qualitative work including in-depth interviews with HIV-positive MSM and focus groups with providers, we developed a tailored intervention and conducted a pilot test to refine intervention materials and procedures.

methodsThe Shikamana intervention combines modified Next-Step Counseling by trained providers, support from a trained peer navigator, and tailored use of SMS messaging, phone calls, and discrete pill carriers. Providers, including counselors and clinicians, work together with peer navigators as a case management team.

resultsForty HIV-positive MSM aged 19-51 participated in intervention development and testing. Six counselors, three clinical officers, and four MSM peers were trained in intervention procedures. Of 10 ART-naïve participants who enrolled in the pilot, eight completed follow-up with no adverse events reported. One participant was lost to follow-up after 2 months and another failed to initiate ART despite ongoing counseling. No adverse events were reported. Staff feedback and exit interviews rated the intervention as feasible and acceptable.

conclusionThis adherence support intervention tailored for Kenyan MSM was well tolerated, feasible, and acceptable in the pilot phase. A randomized controlled trial of a scaled-up programme to estimate intervention efficacy is ongoing.

Indexed as

Patient CompliancePrimary PreventionSecondary PreventionAdultAnti-HIV AgentsCounselingFocus GroupsHIV InfectionsHomosexuality, MaleHumansKenyaMaleMiddle AgedPeer GroupPilot ProjectsStereotypingAnti-HIV Agents

Identifiers

PMID26562813
PMCPMC4706368
OpenAlexW2468434473

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.