ArticleJAMA ophthalmology2016
Variability of Ocular Deviation in Strabismus.
Article in JAMA ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Machine Learning-Based Prediction of Strabismus with and without Amblyopia from Fixation Eye Movements.Ophthalmology science · 2026Article
- Analysis of Convergence and Divergence Using an Eye Tracker in Acquired Comitant Esotropia.Investigative ophthalmology & visual science · 2026Article
- Analysis of Saccade Characteristics During Fusional Vergence Tests in Normal Binocular Vision Participants.Journal of eye movement research · 2026Article
- Pilot comparison of monocular and binocular modes of virtual reality field testing in strabismus.Scientific reports · 2025Article
- Binocular Eye Alignment Monitor (BEAM): Home Monitoring Proof-of-Concept Device to Quantify Binocular Alignment for Intermittent Exotropia.Translational vision science & technology · 2025Article
- Quantitative Assessment of Fixational Disparity Using a Binocular Eye-Tracking Technique in Children with Strabismus.Journal of eye movement research · 2025Article
- Strabismus Detection in Monocular Eye Images for Telemedicine Applications.Journal of imaging · 2024Article
- Multifaceted Interactions of Stereoacuity, Inter-Ocular Suppression, and Fixation Eye Movement Abnormalities in Amblyopia and Strabismus.Investigative ophthalmology & visual science · 2024Article
- A low-cost robotic oculomotor simulator for assessing eye tracking accuracy in health and disease.Behavior research methods · 2024Article
- Cortical Reorganization After Optical Alignment in Strabismic Patients Outside of Critical Period.Investigative ophthalmology & visual science · 2023Article
- Ambulatory Monitoring With Eye Tracking Glasses to Assess the Severity of Intermittent Exotropia.American journal of ophthalmology · 2023Observational
- Commentary: Automated strabismus measurement - Orthoptics with an edge!Indian journal of ophthalmology · 2022Article
- Effect of Viewing Conditions on Fixation Eye Movements and Eye Alignment in Amblyopia.Investigative ophthalmology & visual science · 2022Article
- Quantitative Evaluation of the Association Between Fixation Stability and Phoria During Short-Term Binocular Viewing.Frontiers in neuroscience · 2022Article
- Interocular Suppression in Primary Visual Cortex in Strabismus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- A Dichoptic Optokinetic Nystagmus Paradigm for Interocular Suppression Quantification in Intermittent Exotropia.Frontiers in neuroscience · 2021Article
- Article
- Analysis of Alphabet Patterns of Deviations Found in Patients Without Strabismus in Primary Position.Clinical optometry · 2020Article
- Fixational Eye Movement Waveforms in Amblyopia: Characteristics of Fast and Slow Eye Movements.Journal of eye movement research · 2019Article
- Fixation instability during binocular viewing in anisometropic and strabismic children.Experimental eye research · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
importanceIn strabismus, the fixating eye conveys the direction of gaze while the fellow eye points at a peripheral location in space. The stability of the eyes may be reduced by the absence of a common target.
objectiveTo quantify the stability of eye position in strabismus and to measure variability in the ocular deviation. DESIGN, SETTING, AND
participantsFrom 2010 to 2014, a prospective comparative case study of 25 patients with alternating exotropia with normal visual acuity in each eye and 25 control individuals was conducted in a laboratory at a tertiary eye center. A video eye tracker was used to measure the position of each eye while participants alternated fixation on the center of a cross under dichoptic conditions or scanned pictures of natural scenes. MAIN OUTCOMES AND MEASURES: Spatial and temporal variability in the position of the fixating eye and the nonfixating eye in patients with strabismus and control individuals, quantified by the log area of ellipses containing 95% of eye positions or mean SDs of eye position.
resultsIn the 25 patients with strabismus, the mean (SD) age was 28 (14) years (range, 8-55 years) and the mean (SD) ocular deviation was 14.2° (5.9°) (range, 4.4°-22.4°). In the patients with strabismus, the mean position variability (1.80 log units; 95% CI, 1.66-1.93) for the deviating eye was greater than for the fixating eye (1.26 log units; 95% CI, 1.17-1.35) (P < .001). The fixating eye of patients with strabismus was more variable in position than the fixating eye of individuals without strabismus (0.98 log units; 95% CI, 0.88-1.08) (P < .005). CONCLUSIONS AND RELEVANCE: In patients with strabismus, even without amblyopia, the deviated eye is more variable in position than the fixating eye. Both eyes are less stable in position than the eyes of control individuals, which indicates that strabismus impairs the ability to fixate targets steadily. Saccades contribute to variability of the deviation angle because they are less conjugate in patients with strabismus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.