ArticleScientific reports2015
The complete mitogenome of a 500-year-old Inca child mummy.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Ancient genomes from Ladakh reveal 2800-year-old admixture between Tibetans and South Asians.Science advances · 2026Article
- Ancient genomes from Ladakh reveal 2800-year-old mixture between Tibetans and South Asians.bioRxiv : the preprint server for biology · 2026Article
- The Genomic and Cultural Diversity of the Inka Qhapaq Hucha Ceremony in Chile and Argentina.Genome biology and evolution · 2024Article
- Article
- The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations.Cell host & microbe · 2019Article
- Review
- The Paleo-Indian Entry into South America According to Mitogenomes.Molecular biology and evolution · 2018Article
- Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic movements.Scientific reports · 2017Article
- Phylogenetic and population-based approaches to mitogenome variation do not support association with male infertility.Journal of human genetics · 2017Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In 1985, a frozen mummy was found in Cerro Aconcagua (Argentina). Archaeological studies identified the mummy as a seven-year-old Inca sacrifice victim who lived >500 years ago, at the time of the expansion of the Inca Empire towards the southern cone. The sequence of its entire mitogenome was obtained. After querying a large worldwide database of mitogenomes (>28,000) we found that the Inca haplotype belonged to a branch of haplogroup C1b (C1bi) that has not yet been identified in modern Native Americans. The expansion of C1b into the Americas, as estimated using 203 C1b mitogenomes, dates to the initial Paleoindian settlements (~18.3 thousand years ago [kya]); however, its internal variation differs between Mesoamerica and South America. By querying large databases of control region haplotypes (>150,000), we found only a few C1bi members in Peru and Bolivia (e.g. Aymaras), including one haplotype retrieved from ancient DNA of an individual belonging to the Wari Empire (Peruvian Andes). Overall, the results suggest that the profile of the mummy represents a very rare sub-clade that arose 14.3 (5-23.6) kya and could have been more frequent in the past. A Peruvian Inca origin for present-day C1bi haplotypes would satisfy both the genetic and paleo-anthropological findings.
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