Evidence map›Paper›PMID 26561779›Full record

ReviewLiver international : official journal of the International Association for the Study of the Liver2016

The enteric microbiome in hepatobiliary health and disease.

James H Tabibian, Cyril Varghese, Nicholas F LaRusso, Steven P O'Hara

Open access · bronzeAbstract readReview
In one paragraph

Review in Liver international : official journal of the International Association for the Study of the Liver, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Intercellular Communication between Hepatic Cells in Liver Diseases.International journal of molecular sciences · 2019
    Review
  12. Article
  13. Review
  14. Review
  15. Pathobiology of biliary epithelia.Biochimica et biophysica acta. Molecular basis of disease · 2018
    Review
  16. Review
  17. Review
  18. A Summary of the Second Annual HIV Microbiome Workshop.AIDS research and human retroviruses · 2017
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

James H TabibianDivision of Gastroenterology, University of Pennsylvania, Philadelphia, PA, USA.
Cyril VargheseDepartment of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Nicholas F LaRussoDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Steven P O'HaraDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USUniversity of Pennsylvania · US

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI GREGORY J. GORES · 2009 to 2026
$22.2M
Pathophysiology of Biliary DiseaseR01DK057993 · NIDDK · MAYO CLINIC ROCHESTER · PI LARUSSO, NICHOLAS F., O'HARA, STEVEN P · 2001 to 2025
$7.1M
Pathophysiology of cholangiocyte responses to microbial pathogensR01AI089713 · NIAID · MAYO CLINIC ROCHESTER · PI O'HARA, STEVEN P · 2011 to 2015
$1.8M
NIAID NIH HHS AI089713NIAID NIH HHS R01 AI089713NIDDK NIH HHS DK57993NIDDK NIH HHS P30 DK084567NIDDK NIH HHS P30DK084567NIDDK NIH HHS R01 DK057993
6 · The paper itself

Abstract

Increasing evidence points to the contribution of the intestinal microbiome as a potentially key determinant in the initiation and/or progression of hepatobiliary disease. While current understanding of this dynamic is incomplete, exciting insights are continually being made and more are expected given the developments in molecular and high-throughput omics techniques. In this brief review, we provide a practical and updated synopsis of the interaction of the intestinal microbiome with the liver and its downstream impact on the initiation, progression and complications of hepatobiliary disease.

Indexed as

Gastrointestinal MicrobiomeHealthMicrobiotaAnimalsBiliary TractBiliary Tract DiseasesHost-Pathogen InteractionsHumansInflammation MediatorsIntestinesLiverLiver DiseasesSignal TransductionInflammation Mediatorscholangiopathiescirrhosisliver diseasesmicrobiotatoll-like receptors

Identifiers

PMID26561779
PMCPMC4825184
OpenAlexW2120106574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.