Observational studyThe Journal of pediatrics2016
Global and Regional Derangements of Cerebral Blood Flow and Diffusion Magnetic Resonance Imaging after Pediatric Cardiac Arrest.
Observational study in The Journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Practice patterns for acquiring neuroimaging after pediatric in-hospital cardiac arrest.Resuscitation · 2025Trial
- Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest.Resuscitation · 2026Article
- Machine-learning based prediction of future outcome using multimodal MRI during early childhood.Seminars in fetal & neonatal medicine · 2024Review
- The impact of pediatric post-cardiac arrest care on survival: A multicenter review from the AHA get with the Guidelines®-resuscitation post-cardiac arrest care registry.Resuscitation · 2024Article
- Association between ASL MRI-derived cerebral blood flow and outcomes after pediatric cardiac arrest.Resuscitation · 2024Observational
- Limbic pathway vulnerability associates with neurologic outcome in children after cardiac arrest.Resuscitation · 2023Article
- Introducing advanced neuroimaging into pediatric post-arrest neuroprognostication.Resuscitation · 2023Article
- Early Thalamocortical Reperfusion Leads to Neurologic Recovery in a Rodent Cardiac Arrest Model.Neurocritical care · 2022Article
- Magnetic resonance imaging adds prognostic value to EEG after pediatric cardiac arrest.Resuscitation · 2022Observational
- Association of MRI Brain Injury With Outcome After Pediatric Out-of-Hospital Cardiac Arrest.Neurology · 2021Article
- Neurological Prognostication in Children After Cardiac Arrest.Pediatric neurology · 2020Review
- How can neurological outcomes be predicted in comatose pediatric patients after out-of-hospital cardiac arrest?Clinical and experimental pediatrics · 2020Article
- Report on the Sixth Pediatric Anesthesia Neurodevelopmental Assessment (PANDA) Symposium, "Anesthesia and Neurodevelopment in Children".Journal of neurosurgical anesthesiology · 2019Article
- Alterations in Cerebral Blood Flow after Resuscitation from Cardiac Arrest.Frontiers in pediatrics · 2017Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo quantify and examine the relationship between global and regional cerebral blood flow (CBF) and water diffusion on brain magnetic resonance imaging (MRI) in children after cardiac arrest. STUDY
designChildren admitted to a tertiary care children's hospital from July 2011 to April 2013 who received a brain MRI within 2 weeks after cardiac arrest that included arterial spin labeling and apparent diffusion coefficient (ADC) sequences were studied. CBF and ADC values were calculated globally and in 19 regions of interest. Outcome variables included survival and favorable neurologic outcome, which was defined as Pediatric Cerebral Performance Category ≤3 at 6 months. We examined global and regional relationships between CBF and ADC and their association with outcome.
resultsThis sample included 14 pediatric patients (mean time to MRI 6 ± 4 days), 9 of whom survived and 6 who survived with favorable outcome. Global ADC was significantly decreased in patients with unfavorable outcome (P = .02). Increased CBF and decreased ADC often were colocalized in the same region, especially in children who had unfavorable outcomes.
conclusionsIn this exploratory study, global restricted water diffusion on ADC after pediatric cardiac arrest was associated with unfavorable outcome. MRI assessments of perfusion and diffusion may have prognostic value after pediatric cardiac arrest.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.