ArticleInternational journal of geriatric psychiatry2016
Heterogeneity in the three-year course of major depression among older adults.
Article in International journal of geriatric psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations between loneliness and perceived social support and outcomes of mental health problems: a systematic review.BMC psychiatry · 2018Pooled it
- Transition from depression-free to death in late life: characteristics of bidirectional transitions in depression symptoms.Epidemiology and psychiatric sciences · 2025Article
- Major depressive disorder: hypothesis, mechanism, prevention and treatment.Signal transduction and targeted therapy · 2024Review
- Trajectories of major depression in middle-aged and older adults: A population-based study.International journal of geriatric psychiatry · 2019Article
- The Association Between Juvenile Onset of Depression and Emotion Regulation Difficulties.Frontiers in psychology · 2019Article
- Depressive symptoms and functional decline following coronary interventions in older patients with coronary artery disease: a prospective cohort study.BMC psychiatry · 2016Article
- Correlation between Motor Cortex Excitability Changes and Cognitive Impairment in Vascular Depression: Pathophysiological Insights from a Longitudinal TMS Study.Neural plasticity · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveThe objective of this research was to identify distinct trajectories of recovery in older depressed patients in order to identify optimal samples and points for interventions.
methodsThe sample was 368 patients ages 60 years and older diagnosed with major depression and enrolled in a naturalistic treatment study and followed for up to 3 years.
resultsA model with four trajectory classes fit the data best: a quick recovery class (43%), a persistent moderate symptom class (27%), a persistent high symptom class (15%), and a slow recovery class (15%). Compared with patients in the quick recovery class, patients in the persistent moderate symptom class had more instrumental activities of daily living/mobility limitations and lower levels of subjective social support. Patients in the persistent high symptom class had higher levels of perceived stress and lower levels of social support compared with those with a quick recovery. Patients in the slow recovery class had a younger age of onset compared with those in the quick recovery group. In multinomial logistic regression, levels of perceived stress and social support at baseline significantly differed across classes controlling for demographic and health variables.
conclusionsOlder patients diagnosed with major depression can have varying patterns of response to treatment. Interventions targeting those patients with higher levels of perceived stress and lower levels of subjective social support at the time of the index episode may lead to more favorable long-term trajectories. Copyright © 2015 John Wiley & Sons, Ltd.
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