Evidence map›Paper›PMID 26560534›Full record

ArticleJournal of clinical microbiology2016

HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing.

K Brooks, A DeLong, M Balamane, L Schreier, M Orido, M Chepkenja, E Kemboi, M D'Antuono, P A Chan, W Emonyi and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Dried Spot Paradigm: Problems and Prospects in Proteomics.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

K BrooksDivision of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
A DeLongCenter for Statistical Sciences, School of Public Health, Brown University, Providence, Rhode Island, USA.
M BalamaneDivision of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
L SchreierDivision of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
M OridoAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
M ChepkenjaAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
E KemboiAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
M D'AntuonoDivision of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
P A ChanDivision of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
W EmonyiAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya Department of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
L DieroAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya Department of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
M CoetzerDivision of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
R KantorDivision of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA rkantor@brown.edu.
Brown University · USAMPATH · KEMoi University · KE

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
HIV-1 Drug Resistance in Different SubtypesR01AI066922 · NIAID · STANFORD UNIVERSITY · PI KANTOR, RAMI, KATZENSTEIN, DAVID ALLENBERG · 2008 to 2012
$3.6M
Optimizing HIV Treatment Monitoring under Resource ConstraintsR01AI108441 · NIAID · BROWN UNIVERSITY · PI HOGAN, JOSEPH W, KANTOR, RAMI · 2015 to 2019
$3.5M
Molecular Epidemiology of HIV Transmission NetworksK23AI096923 · NIAID · MIRIAM HOSPITAL · PI CHAN, PHILIP ANDREW · 2011 to 2015
$650k
NIAID NIH HHS K23AI096923NIAID NIH HHS P30 AI042853NIAID NIH HHS P30AI042853NIAID NIH HHS R01 AI108441NIAID NIH HHS R01AI66922NIDA NIH HHS T32DA13911
6 · The paper itself

Abstract

HemaSpot, a novel dried-blood storage filter device, was used for HIV-1 pol resistance testing in 30 fresh United States blood samples and 54 previously frozen Kenyan blood samples. Genotyping succeeded in 79% and 58% of samples, respectively, improved with shorter storage and higher viral load, and had good (86%) resistance mutation concordance to plasma.

Indexed as

DesiccationAdultAgedAged, 80 and overBloodBlood PreservationEquipment and SuppliesFemaleGenotyping TechniquesHIV-1HIV InfectionsHumansMaleMicrobial Sensitivity TestsMiddle AgedSpecimen Handling

Identifiers

PMID26560534
PMCPMC4702722
OpenAlexW2336901972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.