Evidence map›Paper›PMID 26560508›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2016

Prevalence of Post-Traumatic Stress Disorder in Aging Vietnam-Era Veterans: Veterans Administration Cooperative Study 569: Course and Consequences of Post-Traumatic Stress Disorder in Vietnam-Era Veteran Twins.

Jack Goldberg, Kathryn M Magruder, Christopher W Forsberg, Matthew J Friedman, Brett T Litz, Viola Vaccarino, Patrick J Heagerty, Theresa C Gleason, Grant D Huang, Nicholas L Smith

Abstract readTwin Study
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
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  5. The Prevention of Suicide in Older Military Veterans.Behavioral sciences (Basel, Switzerland) · 2025
    Review
  6. The effect of obstructive sleep apnea severity on PTSD symptoms during the course of esketamine treatment: a retrospective clinical study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  7. Characteristics and Correlates of Ten-Year Trajectories of Posttraumatic Stress Symptoms in Older U.S. Military Veterans.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Traumatic disclosures in the life stories of older Vietnam era veterans.Journal of the American Geriatrics Society · 2022
    Article
  13. Post-traumatic Stress Disorder in Older U.S. Military Veterans: Prevalence, Characteristics, and Psychiatric and Functional Burden.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
    Article
  14. Observational
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Jack GoldbergSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, WA; Department of Epidemiology, University of Washington, Seattle, WA. Electronic address: jack.goldberg@va.gov.
Kathryn M MagruderMental Health Service, Ralph H. Johnson VA Medical Center, Charleston, SC; Department of Psychiatry, Medical University of South Carolina, Charleston, SC.
Christopher W ForsbergSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, WA.
Matthew J FriedmanDepartment of Veterans Affairs, National Center for Posttraumatic Stress Disorder, White River Junction, VT; Departments of Psychiatry and Pharmacology & Toxicology, Geisel School of Medicine at Dartmouth, Hanover, NH.
Brett T LitzMassachusetts Epidemiological Research and Information Center, VA Boston Healthcare System, Boston, MA; Boston University School of Medicine, Boston, MA.
Viola VaccarinoDepartments of Epidemiology and Medicine, Emory University, Atlanta, GA.
Patrick J HeagertyDepartment of Biostatistics, University of Washington, Seattle, WA.
Theresa C GleasonCooperative Studies Program, Clinical Science Research and Development, VA Office of Research and Development, Washington, DC.
Grant D HuangCooperative Studies Program, Clinical Science Research and Development, VA Office of Research and Development, Washington, DC.
Nicholas L SmithSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, WA; Department of Epidemiology, University of Washington, Seattle, WA.
VA Puget Sound Health Care System · USVA Office of Research and Development · USBoston University · USEmory University · USMedical University of South Carolina · USNational Center for Post Traumatic Stress Disorder · USUniversity of Washington · US

Funding

Vascular Responses During Mental StressP01HL101398 · NHLBI · EMORY UNIVERSITY · PI SHEPS, DAVID SAMUEL · 2010 to 2015
$11.0M
Mental Stress and Myocardial Ischemia after MI: Sex Differences, Mechanisms and PrognosisR01HL109413 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2012 to 2023
$6.9M
Mechanisms Linking Depression to Cardiovascular RiskR01HL068630 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2001 to 2010
$4.8M
PTSD and Ischemic Heart Disease Progression: A Longitudinal Twin StudyR01HL125246 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2015 to 2018
$3.4M
Posttraumatic Stress Disorder and Cardiovascular DiseaseR01AG026255 · NIA · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2004 to 2007
$2.8M
Mind-Body Interactions in Cardiovascular DiseaseK24HL077506 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2004 to 2013
$1.5M
NHLBI NIH HHS K24 HL077506NHLBI NIH HHS P01 HL101398NHLBI NIH HHS R01 HL068630NHLBI NIH HHS R01 HL109413NHLBI NIH HHS R01 HL125246NIA NIH HHS R01 AG026255
6 · The paper itself

Abstract

objectiveThe prevalence of post-traumatic stress disorder (PTSD) among aging Vietnam-era veterans is not well characterized.

methodsIn a cross-sectional study, 5,598 male Vietnam-era veterans and members of the Vietnam Era Twin Registry were assessed for PTSD using the Composite International Diagnostic Interview. Current symptoms were measured with the PTSD Checklist (PCL). PTSD was estimated according to age (<60 or ≥ 60) and Vietnam theater service.

resultsThe lifetime prevalence of PTSD in theater veterans aged at least 60 years was 16.9% (95% CI: 13.9%-20.5%) and higher than the 5.5% (95% CI: 4.3%-7.0%) among nontheater veterans. Among veterans younger than 60 years, the comparable prevalence was 22.0% for theater (95% CI: 16.7%-28.4%) and 15.7% for nontheater (95% CI: 13.4%-18.2%) veterans. Similar results were found for theater service and current PTSD prevalence (past 12 months). PCL scores were significantly higher in theater compared with nontheater veterans in both younger and older cohorts. In both the younger and older cohorts significant differences in lifetime and current PTSD prevalence and PCL scores persisted in theater service discordant twin pairs.

conclusionVietnam service is related to elevated PTSD prevalence and current symptom burden in aging veterans. More than 30 years after the end of the Vietnam conflict, many veterans continue to suffer from PTSD, which highlights the need for continuing outreach throughout the life course.

Indexed as

AgedAged, 80 and overAgingCross-Sectional StudiesHumansMaleMiddle AgedPrevalenceRegistriesStress Disorders, Post-TraumaticTwinsUnited StatesVeteransVietnam ConflictEpidemiologygeriatric/aging/elderlyPTSD/posttraumatic stress disordertraumatwin studies

Identifiers

PMID26560508
PMCPMC5928006
OpenAlexW253412985

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.