Evidence map›Paper›PMID 26559259›Full record

Observational studyMedicine2015

Frontal Lobe Function and Risk of Hip Fracture in Patient With Alzheimer Disease: An Analysis of Linked Data.

Hyun Woong Roh, Chang Hyung Hong, SooJin Lee, Yunhwan Lee, Kang Soo Lee, Ki Jung Chang, Byoung Hoon Oh, Seong Hye Choi, Seong Yoon Kim, Joung Hwan Back and 4 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Quad-phased data mining modeling for dementia diagnosis.BMC medical informatics and decision making · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hyun Woong RohFrom the Department of Psychiatry, Ajou University School of Medicine, Suwon (HWR, CHH, KJC, YKC, KYL, JSN, SJS); Health Administration, Department of Management & Administration, Backseok Arts University, Seoul (SJL); Department of Preventive Medicine and Public Health, Ajou University School of Medicine (YL); Institute on Aging, Ajou University Medical Center, Suwon (HWR, CHH, YL, KJC, SJS); Department of Psychiatry, CHA University College of Medicine, Gangnam Medical Center and CHAUM Life Center (KSL); Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul (BHO); Department of Neurology, Inha University School of Medicine, Incheon (SHC); Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul (SYK); and Health Insurance Police Research Institute, National Health Insurance Service, Seoul, Republic of Korea (JHB).
Chang Hyung Hong
SooJin Lee
Yunhwan Lee
Kang Soo Lee
Ki Jung Chang
Byoung Hoon Oh
Seong Hye Choi
Seong Yoon Kim
Joung Hwan Back
Young Ki Chung
Ki Young Lim
Jai Sung Noh
Sang Joon Son

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the association between frontal lobe function and risk of hip fracture in patients with Alzheimer disease (AD).Retrospective cohort study using multicenter hospital-based dementia registry and national health insurance claim data was done. Participants who had available data of neuropsychological test, national health insurance claim, and other covariates were included. A total of 1660 patients with AD were included based on Stroop Test results. A total of 1563 patients with AD were included based on the Controlled Oral Word Association Test (COWAT) results. Hip fracture was measured by validated identification criteria using national health insurance claim data. Frontal lobe function was measured by Stroop Test and COWAT at baseline.After adjusting for potential covariates, including cognitive function in other domains (language, verbal and nonverbal memory, and attention), the Cox proportional hazard regression analysis revealed that risk of a hip fracture was decreased with a hazard ratio (HR) of 0.98 per one point of increase in the Stroop Test (adjusted HR = 0.98, 95% confidence interval [CI]: 0.97-1.00) and 0.93 per one point increase in COWAT (adjusted HR = 0.93, 95% CI: 0.88-0.99).The risk of hip fracture in AD patients was associated with baseline frontal lobe function. The result of this research presents evidence of association between frontal lobe function and risk of hip fracture in patients with AD.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseFemaleFrontal LobeHip FracturesHumansMaleNeuropsychological TestsProportional Hazards ModelsRetrospective StudiesRisk Factors

Identifiers

PMID26559259
PMCPMC4912253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.