Evidence map›Paper›PMID 26558424›Full record

ReviewExpert review of proteomics2016

Immunocapture strategies in translational proteomics.

Claudia Fredolini, Sanna Byström, Elisa Pin, Fredrik Edfors, Davide Tamburro, Maria Jesus Iglesias, Anna Häggmark, Mun-Gwan Hong, Mathias Uhlen, Peter Nilsson and 1 more

Abstract readReview
In one paragraph

Review in Expert review of proteomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Plasma/Serum Proteomics based on Mass Spectrometry.Protein and peptide letters · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Liquid Chromatography-Mass Spectrometry for Clinical Metabolomics: An Overview.Advances in experimental medicine and biology · 2021
    Article
  12. Article
  13. Rebooting Human Immunology.Annual review of immunology · 2018
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claudia Fredolinia Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Sanna Byströma Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Elisa Pina Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Fredrik Edforsa Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Davide Tamburrob Department of Oncology-Pathology, Clinical Proteomics Mass Spectrometry, SciLifeLab , Karolinska Institutet , Solna , Sweden.
Maria Jesus Iglesiasa Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Anna Häggmarka Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Mun-Gwan Honga Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Mathias Uhlena Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Peter Nilssona Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.
Jochen M Schwenka Affinity Proteomics, SciLifeLab, School of Biotechnology , KTH - Royal Institute of Technology , Solna , Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aiming at clinical studies of human diseases, antibody-assisted assays have been applied to biomarker discovery and toward a streamlined translation from patient profiling to assays supporting personalized treatments. In recent years, integrated strategies to couple and combine antibodies with mass spectrometry-based proteomic efforts have emerged, allowing for novel possibilities in basic and clinical research. Described in this review are some of the field's current and emerging immunocapture approaches from an affinity proteomics perspective. Discussed are some of their advantages, pitfalls and opportunities for the next phase in clinical and translational proteomics.

Indexed as

AnimalsAntibodiesHumansImmunoprecipitationLimit of DetectionMass SpectrometryProtein BindingProteomeProteomicsTranslational Research, BiomedicalAntibodiesProteomeAntibodiesimmunocapturemass spectrometryprotein enrichmentsandwich assaysSRM

Identifiers

PMID26558424
PMCPMC4732419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.