ArticleThe American journal of case reports2015
An Autopsy Case of Rapidly Progressing Spindle Cell Carcinoma of the Lung Accompanied with Intratumor Hemorrhage.
Article in The American journal of case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 8 citations in OpenAlex.
- Development and validation of a prognostic predictive model of pulmonary spindle cell carcinoma from the surveillance, epidemiology and end results database.Translational cancer research · 2022Article
- Clinical case of lung spindle cell carcinoma markedly responsive to pembrolizumab.Thoracic cancer · 2021Article
- Long-term survival in a patient with pulmonary spindle cell carcinoma treated with traditional Chinese medicine.BMJ case reports · 2018Article
- Pulmonary spindle cell carcinoma with unusual morphology: A rare case report and review of the literature.Medicine · 2017Review
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5 authors at 1 institution in 1 country.
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Abstract
backgroundSpindle cell carcinoma (SPCC) of the lung is a subset of sarcomatoid carcinoma. Its clinical features are unclear because of its rarity. Here, we report an autopsy case of SPCC and review CT findings and chemotherapeutic regimens based on previous reports of this disease. To our knowledge, this is the first reported case of pemetrexed used to treat SPCC. CASE REPORT: A 74-year-old Japanese male presented with dyspnea and contrast-enhanced computed tomography (CT) showed abundant left pleural effusion and a mass in lower lobe of the left lung. By the tumor biopsy, he was diagnosed for SPCC of the lung, cT3N0M1a, stage IV. The tumor was resistant to chemotherapy with carboplatin and pemetrexed, and rapidly progressed. Autopsy revealed abundant hemorrhage within the tumor, which apparently reflects a low-density area in CT.
conclusionsPresent case and the accumulation of cases indicate that low-density areas in CT and rapid tumor progression may be common SPCC findings.
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