SynthesisBioMed research international2015
The Impact of Pain Assessment on Critically Ill Patients' Outcomes: A Systematic Review.
Synthesis in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- The effect of music on pain in mechanically ventilated patients: A Systematic review.Nursing in critical care · 2025Pooled it
- European Society of Intensive Care Medicine guidelines on end of life and palliative care in the intensive care unit.Intensive care medicine · 2024Guideline
- Evidence of internal structure validity of the nursing outcome "Mechanical Ventilation Weaning Response: Adult (0412)" for critically ill COVID-19 patients.International journal of nursing knowledge · 2026Article
- Early Use of Fentanyl Increases Risk of Delirium in Patients Transfer to the intensive Care Unit After Cardiac Surgery Immediately: A Target Trial Emulation.Journal of evidence-based medicine · 2026Article
- The Critical Care Pain Observation Tool for Families (CPOT-Fam).Canadian journal of pain = Revue canadienne de la douleur · 2026Article
- Nociception and pain assessment during suctioning procedures in mechanically ventilated patients in the intensive care unit: A validation study of the Nociception Level index (NOL™).Canadian journal of pain = Revue canadienne de la douleur · 2026Article
- Validation of the Nociception Level Index for the Detection of Nociception and Pain in Critically Ill Adults: Protocol for an Observational Study.JMIR research protocols · 2025Article
- Diurnal Pain Classification in Critically Ill Patients using Machine Learning on Accelerometry and Analgesic Data.IEEE International Conference on Bioinformatics and Biomedicine workshops. IEEE International Conference on Bioinformatics and Biomedicine · 2023Article
- PERSONALISED PAIN TREATMENT IN INTENSIVE CARE UNITS - MONITORING OF NOCICEPTION.Acta clinica Croatica · 2023Review
- Pain assessment in intensive care units of a low-middle income country: impact of the basic educational course.BMC medical education · 2023Article
- Clinical utility of automatic phenotype annotation in unstructured clinical notes: intensive care unit use.BMJ health & care informatics · 2022Article
- Pain assessment and analgesic management in patients admitted to intensive care: an Australian and New Zealand point prevalence study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2022Article
- Study protocol: development and pilot testing of the Critical Care Pain Observation Tool for families (CPOT-Fam).Pilot and feasibility studies · 2022Article
- Validation Testing of the European Portuguese Critical-Care Pain Observation Tool.Healthcare (Basel, Switzerland) · 2022Article
- Pain Behavior Experienced During Nursing Interventions by Patients on Mechanical Ventilation: A Cross-Sectional Study.Florence Nightingale journal of nursing · 2022Article
- Pain management of nalbuphine and sufentanil in patients admitted intensive care unit of different ages.BMC emergency medicine · 2022Article
- Deep Learning-Based Pain Classifier Based on the Facial Expression in Critically Ill Patients.Frontiers in medicine · 2022Article
- The Effect of Various, Everyday Practices on Glucose Levels in Critically Ill Children.Journal of diabetes science and technology · 2022Article
- A prospective comparison between multidisciplinary healthcare providers' clinical examination and a validated pain scale.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Pain Control and Opioid Use in ICU should be a Quality Parameter.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In critically ill patients, pain is a major problem. Efficient pain management depends on a systematic, comprehensive assessment of pain. We aimed to review and synthesize current evidence on the impact of a systematic approach to pain assessment on critically ill patients' outcomes. A systematic review of published studies (CINAHL, PUBMED, SCOPUS, EMBASE, and COCHRANE databases) with predetermined eligibility criteria was undertaken. Methodological quality was assessed by the EPHPP quality assessment tool. A total of 10 eligible studies were identified. Due to big heterogeneity, quantitative synthesis was not feasible. Most studies indicated the frequency, duration of pain assessment, and types of pain assessment tools. Methodological quality assessment yielded "strong" ratings for 5/10 and "weak" ratings for 3/10 studies. Implementation of systematic approaches to pain assessment appears to associate with more frequent documented reports of pain and more efficient decisions for pain management. There was evidence of favorable effects on pain intensity, duration of mechanical ventilation, length of ICU stay, mortality, adverse events, and complications. This systematic review demonstrates a link between systematic pain assessment and outcome in critical illness. However, the current level of evidence is insufficient to draw firm conclusions. More high quality randomized clinical studies are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.