Evidence map›Paper›PMID 26558246›Full record

ArticleAutopsy & case reports

Acute Hemorrhagic Edema of Infancy: an unusual diagnosis for the general pediatrician.

Diego Fontana Siqueira Cunha, Ana Letícia Fornazieri Darcie, Gabriel Nuncio Benevides, Angela Espósito Ferronato, Noely Hein, Denise Swei Lo, Cristina Ryoka Miyao Yoshioka, Maki Hirose, Debora Morais Cardoso, Alfredo Elias Gilio

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Autopsy & case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Observational
  2. Acute hemorrhagic edema of infancy: a rare case report from Syria.Annals of medicine and surgery (2012) · 2023
    Article
  3. Article
  4. Coronavirus Disease 2019 and Acute Hemorrhagic Edema of Infancy.Case reports in infectious diseases · 2022
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Diego Fontana Siqueira CunhaDepartment of Pediatrics - Hospital das Clínicas - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil .
Ana Letícia Fornazieri DarcieFaculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil .
Gabriel Nuncio BenevidesFaculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil .
Angela Espósito FerronatoDivision of Pediatrics - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil .
Noely HeinDivision of Pediatrics - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil .
Denise Swei LoDivision of Pediatrics - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil .
Cristina Ryoka Miyao YoshiokaDivision of Pediatrics - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil .
Maki HiroseDivision of Pediatrics - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil .
Debora Morais CardosoDivision of Pediatrics - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil .
Alfredo Elias GilioFaculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil . ; Division of Pediatrics - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil .
Hospital Universitário da Universidade de São Paulo · BRUniversidade de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute Hemorrhagic Edema of Infancy (AHEI) is a rare leukocytoclastic vasculitis, clinically characterized by the classical triad: palpable purpuric skin lesions, edema and fever, and is commonly misdiagnosed as Henoch-Schönlein purpura. In addition to its sudden onset, AHEI is also characterized by its self-limited course with complete and spontaneous recovery occurring between 1 and 3 weeks. Because of the scarcity of studies on therapy with corticosteroids, the conservative approach is usually recommended. The authors report an unusual case of an one-year-old boy who presented with typical cutaneous rash of AHEI and orchitis, the latter showing complete resolution after less than 24 hours of prednisolone therapy. The authors call attention to this entity mainly as a differential diagnosis of Henoch-Schönlein purpura and to the importance of new studies to establish the benefits of corticosteroid therapy for AHEI.

Indexed as

InfantOrchitisPurpuraSteroidsVasculitis, Leukocytoclastic, Cutaneous

Identifiers

PMID26558246
PMCPMC4636105
OpenAlexW2183215530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.