ArticleInternational journal of ophthalmology2015
Anterior segment changes after pharmacologic mydriasis using Pentacam and optical coherence tomography in angle closure suspects.
Article in International journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Validation of an Artificial Intelligence-Based Anterior Chamber Depth Estimation Using a Smartphone-Compatible Slit Lamp Device.Ophthalmology science · 2026Article
- The Effect of Physical Activity on Anterior Segment Structures and the Retinal Nerve Fiber Layer: A Comparison of Elite Athletes and Sedentary Individuals.Medicina (Kaunas, Lithuania) · 2025Observational
- Changes in Ocular Biometry After Pharmacologic Cycloplegia and Mydriasis in Primary Angle Closure Disease.Ophthalmology and therapy · 2025Article
- Investigation of Age-Related Changes in Iris Curvature Among Japanese Participants.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Repeatability and Agreement of Central Vault for Implantable Collamer Lens Obtained by the Tomey OA-2000 Biometer and Spectralis OCT.Journal of ophthalmology · 2024Article
- Assessment of iris volume in glaucoma patients with type 2 diabetes mellitus by AS-OCT.International journal of ophthalmology · 2023Article
- Detection of occludable angle with anterior segment optical coherence tomography and Pentacam as non-contact screening methods.International ophthalmology · 2022Observational
- Comparison of a New Optical Biometer That Combines Scheimpflug Imaging With Partial Coherence Interferometry With That of an Optical Biometer Based on Swept-Source Optical Coherence Tomography and Placido-Disk Topography.Frontiers in medicine · 2021Article
- Comparative Study of the Effects of 1% Atropine on the Anterior Segment.Journal of ophthalmology · 2020Article
- Comparative study of anterior segment measurements using 3 different instruments in myopic patients after ICL implantation.BMC ophthalmology · 2019Article
- Influence of exercise on the structure of the anterior chamber of the eye.Acta ophthalmologica · 2018Article
- Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes.Journal of ophthalmology · 2018Article
- Associated factors of acute primary angle closure glaucoma in a sub-group of Chinese people: comparison between attack eyes and normal controls.Scientific reports · 2017Article
- Effects of phacoemulsification and intraocular lens implantation combined with ciliarotomy in the treatment of angle-closure glaucoma with cataract.Experimental and therapeutic medicine · 2016Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare the dynamic changes of anterior segment parameters especially iris morphology induced by pharmacologic mydriasis between angle closure suspects and normal controls.
methodsThe study group comprised 19 eyes of 19 angle closure suspects and 19 eyes of 19 age- and sex-matched normal open-angle eyes. Pentacam and optical coherence tomography measurements before and 30min after instillation of compound tropicamide eye drop were performed and compared. Biometric evaluations of iris tomography and anterior chamber angle were estimated by a customized image-processing software.
resultsBaseline axial length, iris cross sectional area and volume did not differ significantly between angle closure suspects and normal controls. Angle closure suspects had smaller pupil size, narrower anterior segment dimension and axial length, thinner iris with greater curve in comparison with normal controls. Pharmacologic mydriasis led to significant increments in iris thickness at 750 µm, anterior chamber depth and volume, whereas significant decrements in iris curve, cross sectional area and volume in both groups. Angle opening distance at 500 µm was increased significantly in normal controls (from 0.465±0.115 mm to 0.539±0.167 mm, P=0.009), but not in angle closure suspects (from 0.125±0.100 mm to 0.145±0.131 mm, P=0.326). Iris volume change per millimeter of pupil dilation (ΔIV/ΔPD) decreased significantly less in angle closure suspects than normal controls (-2.47±1.33 mm(2) vs -3.63±1.58 mm(2), P=0.019). Linear regression analysis showed that the change of angle opening distance at 500 µm was associated most with the change of central anterior chamber depth (β=0.841, P=0.002) and ΔIV/ΔPD (β=0.028, P=0.002), followed by gender (β=0.062, P=0.032).
conclusionSmaller iris volume decrement per millimeter of pupil dilation is related significantly with the less anterior angle opening in angle closure suspects after pharmacologic mydriasis. Dynamic iris change may be as a prospective indicator of iris compressibility and angle closure glaucoma.
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