Evidence map›Paper›PMID 26557977›Full record

ArticleBiology of sex differences2015

Sex differences in substance use, health, and social functioning among opioid users receiving methadone treatment: a multicenter cohort study.

Monica Bawor, Brittany B Dennis, Michael Varenbut, Jeff Daiter, David C Marsh, Carolyn Plater, Andrew Worster, Meir Steiner, Rebecca Anglin, Guillaume Pare and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology of sex differences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Monica BaworMiNDS Neuroscience Graduate Program, McMaster University, Hamilton, Ontario Canada ; St. George's, University of London, London, UK ; Population Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, Ontario Canada ; Peter Boris Centre for Addiction Research, St. Joseph's Healthcare Hamilton, Hamilton, Ontario Canada.
Brittany B DennisSt. George's, University of London, London, UK ; Population Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, Ontario Canada ; Peter Boris Centre for Addiction Research, St. Joseph's Healthcare Hamilton, Hamilton, Ontario Canada ; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario Canada.
Michael VarenbutCanadian Addiction Treatment Centres (CATC), Richmond Hill, Ontario Canada.
Jeff DaiterCanadian Addiction Treatment Centres (CATC), Richmond Hill, Ontario Canada.
David C MarshCanadian Addiction Treatment Centres (CATC), Richmond Hill, Ontario Canada ; Northern Ontario School of Medicine, Laurentian Campus, Sudbury, Ontario Canada.
Carolyn PlaterCanadian Addiction Treatment Centres (CATC), Richmond Hill, Ontario Canada.
Andrew WorsterDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario Canada ; Canadian Addiction Treatment Centres (CATC), Richmond Hill, Ontario Canada ; Department of Medicine, McMaster University, Hamilton, Ontario Canada.
Meir SteinerDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario Canada ; Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, Ontario Canada ; Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario Canada.
Rebecca AnglinDepartment of Medicine, McMaster University, Hamilton, Ontario Canada ; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario Canada.
Guillaume ParePopulation Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, Ontario Canada ; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario Canada.
Dipika DesaiPopulation Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, Ontario Canada.
Lehana ThabaneDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario Canada ; Biostatistics Unit, Centre for Evaluation of Medicine, Hamilton, Ontario Canada.
Zainab SamaanPopulation Genomics Program, Chanchlani Research Centre, McMaster University, Hamilton, Ontario Canada ; Peter Boris Centre for Addiction Research, St. Joseph's Healthcare Hamilton, Hamilton, Ontario Canada ; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario Canada ; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario Canada ; Mood Disorders Program, St. Joseph's Healthcare, 100 West 5th Street, Hamilton, Ontario L8N 3K7 Canada.
McMaster University · CAPopulation Health Research Institute · CASt George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the growing numbers of men and women with opioid use disorder in Canada, sex-specific issues in treatment have not been re-examined in the current population of patients with opioid addiction. We aimed to evaluate sex differences in substance use, health, and social functioning among men and women currently receiving methadone treatment for opioid use disorder in Ontario, Canada.

methodsWe recruited 503 participants with opioid dependence disorder receiving methadone maintenance treatment. We collected data on demographics, treatment characteristics, psychiatric history, addiction severity, and drug use patterns through urinalysis. We performed adjusted univariate analyses and logistic regression to identify distinct factors affecting men and women.

resultsAmong our sample of 54 % (n = 266) men and 46 % women (n = 226) with mean age 38.3 years, less than half of participants were employed (35.6 %) and married (31.8 %) and had completed a high school education (27.9 %). Compared to men, women had frequent physical and psychological health problems, family history of psychiatric illness, and childcare responsibilities and began using opioids through a physician prescription. Men had higher rates of employment, cigarette smoking, and cannabis use compared to women.

conclusionsOur results have revealed different patterns of substance use, health, and social functioning among men and women currently receiving methadone treatment for opioid addiction in Ontario, Canada. This information can be used to develop an integrative treatment regimen that caters to the individual needs of men and women, as well as to inform methadone treatment protocols to include specialized services (including vocational counseling, childcare and parenting assistance, medical assistance, relationship or domestic violence counseling, etc.) and increase their availability and accessibility on a larger scale.

Indexed as

Methadone maintenance treatmentOpioid addictionSex differencesSubstance use disordersWomen’s health

Identifiers

PMID26557977
PMCPMC4640383
OpenAlexW2179881786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.